Department of Anesthesiology, West China Hospital of Sichuan University, Chengdu, China.
Perfusion. 2024 Apr;39(3):445-451. doi: 10.1177/02676591221151028. Epub 2023 Feb 3.
Complications after cardiac surgery with cardiopulmonary bypass (CPB) are associated with increased morbidity and mortality. Early detection and prompt reversion of tissue hypoperfusion during CPB are key factors to reduce organ dysfunction after cardiac surgery. CO (carbon dioxide)-derived variables which are easy to assess and routinely available to evaluate the adequacy of macro- and microcirculation may offer important information on the adequacy of the perfusion during CPB. However, since some practical issues remain unsolved in providing a reliable measurement of CO removal from the patient, CO-derived variables are not widely monitoring during CPB. This review aims to demonstrate the basic principles of CO-derived variables during CPB, the available techniques to assess CO-derived variables on CPB and the clinically relevant applications.
体外循环（CPB）心脏手术后的并发症与发病率和死亡率的增加有关。在 CPB 期间，早期发现和及时纠正组织低灌注是减少心脏手术后器官功能障碍的关键因素。CO（二氧化碳）衍生变量易于评估，并且常规可用于评估大循环和微循环的充分性，可能提供有关 CPB 期间灌注充分性的重要信息。然而，由于在从患者身上可靠地测量 CO 去除方面存在一些实际问题，因此 CO 衍生变量在 CPB 期间并未得到广泛监测。本综述旨在展示 CPB 期间 CO 衍生变量的基本原理、评估 CPB 期间 CO 衍生变量的可用技术以及临床相关应用。
