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在伦敦一家教学医院的 9 年期间,见证派信徒的产科结局:病例系列。

Obstetric outcomes in Jehovah's Witnesses: case series over nine years in a London teaching hospital.

机构信息

Department of Obstetrics and Gynaecology, North Middlesex University Hospital, London, UK.

St. George's International School of Medicine, St. George's, Grenada.

出版信息

Arch Gynecol Obstet. 2024 Feb;309(2):475-481. doi: 10.1007/s00404-023-06940-x. Epub 2023 Feb 3.

DOI:10.1007/s00404-023-06940-x
PMID:36735030
Abstract

OBJECTIVES

The aim of the study is to assess obstetric and fetal outcomes of Jehovah's Witnesses (JWs) mothers in an inner city teaching hospital, as well as to examine the acceptance rates of various blood fractions and blood transfusion alternatives.

METHODS

Case series to evaluate the maternal and fetal outcomes of JWs over a nine period between 2013 and 2021.

RESULTS

There were 146 pregnancies extracted from our database, of which 10 were early pregnancy losses. Data from 136 deliveries > 24 weeks' gestation were assessed, with a mean maternal age and gestational age of 30.26 (± 5.4) years and 38.7 (± 5.3) weeks, respectively. 57% had normal vaginal deliveries, 8% had instrumental births and 35% had caesarean births. Mean estimated blood loss at caesarean was 575 (± 305.6) mls, while the overall mean estimated loss was 427.8 (± 299.8) mls. Cell salvage was performed in all caesarean sections but autologous transfusion was only necessary for 26%. Consultant presence was documented in 62% of caesarean births. The mean birthweight and 5-min Apgar scores were 3.31 (± 0.05) kg and 9.1 (± 0.09), respectively. There were no maternal deaths or admissions to the adult intensive care unit and the most serious complication was a uterine rupture following a trial of scar, after which the baby required cooling for hypoxic ischaemic encephalopathy.

CONCLUSIONS

Pregnant JWs received obstetric care led by senior clinicians, with optimisation of haematinics, minimizing of blood loss at delivery and access to technology such as cell salvage.

摘要

目的

本研究旨在评估在一家市区教学医院中,作为耶和华见证人的母亲的产科和胎儿结局,以及检查各种血液成分和输血替代物的接受率。

方法

这是一项病例系列研究,评估了 2013 年至 2021 年期间的 9 个时期内的耶和华见证人的母亲的母婴结局。

结果

从我们的数据库中提取了 146 例妊娠,其中 10 例为早期妊娠丢失。评估了 136 例>24 周分娩的数据,产妇的平均年龄和妊娠年龄分别为 30.26(±5.4)岁和 38.7(±5.3)周。57%为正常阴道分娩,8%为器械分娩,35%为剖宫产。剖宫产术中平均估计出血量为 575(±305.6)毫升,而总平均估计出血量为 427.8(±299.8)毫升。所有剖宫产术中均进行了细胞回收,但仅 26%需要自体输血。记录了 62%的剖宫产术有顾问在场。平均出生体重和 5 分钟 Apgar 评分分别为 3.31(±0.05)kg 和 9.1(±0.09)。没有产妇死亡或入住成人重症监护病房,最严重的并发症是疤痕试产后子宫破裂,随后婴儿因缺氧缺血性脑病需要冷却。

结论

接受妊娠的耶和华见证人由资深临床医生提供产科护理,优化血液成分,减少分娩时的出血量,并可使用细胞回收等技术。

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本文引用的文献

1
Women who decline blood during labour: Review of findings and lessons learnt from 52 years of Confidential Enquiries into maternal mortality in the United Kingdom (1962-2019).产妇拒绝输血:对英国 52 年母婴死亡机密调查报告(1962-2019 年)中发现的结果和吸取的经验教训的回顾。
Eur J Obstet Gynecol Reprod Biol. 2022 Apr;271:20-26. doi: 10.1016/j.ejogrb.2022.01.028. Epub 2022 Feb 1.
2
Obstetric outcomes and acceptance of alternative therapies to blood transfusion by Jehovah's Witnesses in Japan: a single-center study.日本耶和华见证会信徒的产科结局及对输血替代疗法的接受情况:一项单中心研究
Int J Hematol. 2018 Oct;108(4):432-437. doi: 10.1007/s12185-018-2490-7. Epub 2018 Jun 29.
3
Preferences of Jehovah's Witnesses regarding haematological supports in an obstetric setting: experience of a single university teaching hospital.
耶和华见证人在产科环境中对血液学支持的偏好:一家大学教学医院的经验
Int J Obstet Anesth. 2016 Feb;25:53-7. doi: 10.1016/j.ijoa.2015.09.005. Epub 2015 Sep 25.
4
Maternal mortality and serious maternal morbidity in Jehovah's witnesses in The Netherlands.荷兰耶和华见证人的孕产妇死亡率和严重孕产妇发病率。
BJOG. 2009 Jul;116(8):1103-8; discussion 1108-10. doi: 10.1111/j.1471-0528.2009.02191.x.
5
Obstetric care of Jehovah's Witnesses: a 14-year observational study.耶和华见证人的产科护理:一项为期14年的观察性研究。
Arch Gynecol Obstet. 2007 Oct;276(4):339-43. doi: 10.1007/s00404-007-0346-0. Epub 2007 May 24.
6
Responses by pregnant Jehovah's Witnesses on health care proxies.怀孕的耶和华见证人对医疗保健代理人的回应。
Obstet Gynecol. 2004 Sep;104(3):541-4. doi: 10.1097/01.AOG.0000135276.25886.8e.
7
A criterion audit of women's awareness of blood transfusion in pregnancy.一项关于孕期女性输血意识的标准审核。
BMC Pregnancy Childbirth. 2002 Sep 25;2(1):7. doi: 10.1186/1471-2393-2-7.
8
Are women who are Jehovah's Witnesses at risk of maternal death?耶和华见证人的女性会面临孕产妇死亡风险吗?
Am J Obstet Gynecol. 2001 Oct;185(4):893-5. doi: 10.1067/mob.2001.117357.