Monchaud David
Institut de Chimie Moléculaire, ICMUB CNRS UMR 6302, UBFC, Dijon, France.
Mol Cell. 2023 Feb 2;83(3):330-331. doi: 10.1016/j.molcel.2022.12.010.
Roschdi et al. report on a new, higher-order RNA structure folding from an alternating uridine (U)/guanosine (G) repeated sequence-the pUG tail-into a peculiar G-quadruplex structure-the pUG fold-found to orchestrate the gene-silencing activity of pUGylated RNAs.
罗施迪等人报告了一种新的高阶RNA结构，它由交替的尿苷（U）/鸟苷（G）重复序列——pUG尾——折叠成一种特殊的G-四链体结构——pUG折叠，该结构被发现可协调pUG化RNA的基因沉默活性。
