用于细胞保护和近红外光动力应用的超稳定碲掺杂碳量子点
Ultra-stable tellurium-doped carbon quantum dots for cell protection and near-infrared photodynamic application.
作者信息
Chen Hao, Wen Kaikai, Chen Jingya, Xing Wang, Wu Xiaoxi, Shi Qinqin, Peng Aidong, Huang Hui
机构信息
Center of Materials Science and Opto-electronic Technology, College of Materials Science and Opto-electronic Technology & CAS Center for Excellence in Topological Quantum Computation & CAS Key Laboratory of Vacuum Physics, University of Chinese Academy of Sciences, Beijing 100049, China.
Center of Materials Science and Opto-electronic Technology, College of Materials Science and Opto-electronic Technology & CAS Center for Excellence in Topological Quantum Computation & CAS Key Laboratory of Vacuum Physics, University of Chinese Academy of Sciences, Beijing 100049, China; Key Laboratory of Flexible Electronics (KLOFE), Institute of Advanced Materials (IAM), Jiangsu National Synergetic Innovation Center for Advanced Materials (SICAM), Nanjing Tech University, Nanjing 211816, China.
出版信息
Sci Bull (Beijing). 2020 Sep 30;65(18):1580-1586. doi: 10.1016/j.scib.2020.05.021. Epub 2020 May 26.
It is important to regulate the concentration of reactive oxygen species (ROS) in cells since they play important roles in metabolism. Thus, developing nanoreagents to control the ROS is critical. Herein, tellurium-doped carbon quantum dots (Te-CDs) were developed by a simple and efficient hydrothermal method, which can scavenge HO to protect cells under ambient condition, but generate ·OH under 808 nm irradiation as photodynamic application. This contribution presented a kind of novel CDs with dual-functions, which can potentially regulate ROS under different conditions.
调节细胞中活性氧（ROS）的浓度很重要，因为它们在新陈代谢中发挥着重要作用。因此，开发用于控制ROS的纳米试剂至关重要。在此，通过一种简单高效的水热法制备了碲掺杂碳量子点（Te-CDs），其在环境条件下可以清除HO以保护细胞，但在808 nm照射下作为光动力应用会产生·OH。本研究提出了一种具有双重功能的新型碳量子点，其有可能在不同条件下调节ROS。
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