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使用瞬膜瓣治疗两匹马的角膜溃疡和大泡性角膜病变

Treatment of corneal ulceration and bullous keratopathy using a nictitating membrane flap in two horses.

作者信息

Burn Jessica B

机构信息

VCA Central Victoria Veterinary Hospital, Victoria, British Columbia, Canada.

出版信息

Vet Ophthalmol. 2023 Mar;26(2):155-160. doi: 10.1111/vop.13062. Epub 2023 Feb 3.

Abstract

OBJECTIVE

The aim of this study was to describe placement of a nictitating membrane flap as a treatment for corneal ulceration and bullous keratopathy in two horses.

ANIMALS STUDIED

A 13-year-old American Saddlebred mare presented for severe corneal edema, superficial stromal ulceration, and a central bulla of the left eye. A 4-year-old Trakhener stallion also presented with a large axial bulla of the left eye with concurrent severe corneal edema and a deep stromal ulcer.

PROCEDURE

A complete ophthalmic examination was performed. Samples were obtained for corneal cytology, and both horses were started on aggressive medical therapy. Both underwent general anesthesia for placement of a nictitating membrane flap and a subpalpebral lavage system (SPLS).

RESULTS

Corneal cytology for each horse revealed a mixed bacterial population. Moderate Pseudomonas aeruginosa was cultured from the mare, while Aspergillus species and a few Enterococcus gallinarum were cultured from the stallion. The bullae in both horses resolved at 3 and 4 weeks and vision returned in the affected eye 4.5 and 3 months postoperatively at the last follow-up, respectively.

CONCLUSION

Aggressive medical management with concurrent placement of a nictitating membrane flap is effective to treat bullous keratopathy in two horses. The described treatments could be used to treat horses that develop severe or progressive bullous corneal lesions.

摘要

目的

本研究的目的是描述在两匹马中放置瞬膜瓣作为治疗角膜溃疡和大泡性角膜病变的方法。

研究动物

一匹13岁的美国鞍马母马因左眼严重角膜水肿、浅层基质溃疡和中央大泡就诊。一匹4岁的特拉肯纳种公马也因左眼有一个大的轴向大泡,同时伴有严重角膜水肿和深层基质溃疡而就诊。

步骤

进行了全面的眼科检查。采集样本进行角膜细胞学检查,两匹马均开始接受积极的药物治疗。两匹马均接受全身麻醉以放置瞬膜瓣和睑下冲洗系统(SPLS)。

结果

每匹马的角膜细胞学检查均显示有混合细菌群。从母马中培养出中度铜绿假单胞菌,而从种公马中培养出曲霉菌属和一些鹑鸡肠球菌。两匹马的大泡分别在3周和4周时消退,在最后一次随访时,患眼分别在术后4.5个月和3个月恢复视力。

结论

积极的药物治疗并同时放置瞬膜瓣可有效治疗两匹马的大泡性角膜病变。所描述的治疗方法可用于治疗出现严重或进行性大泡性角膜病变的马匹。

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