Leon H. Charney Division of Cardiology, Cardiac Electrophysiology, NYU Langone Health, New York University Grossman School of Medicine, New York, USA.
J Cardiovasc Electrophysiol. 2023 Apr;34(4):800-807. doi: 10.1111/jce.15839. Epub 2023 Feb 14.
Radiofrequency ablation technology for treating atrial fibrillation (AF) has evolved rapidly over the past decade. We investigated the impact of technological and procedural advances on procedure times and ablation outcomes at a major academic medical center over a 10-year period.
Clinical data was collected from patients who presented to NYU Langone Health between 2011 and 2021 for a first-time AF ablation. Time to redo AF ablation or direct current cardioversion (DCCV) for recurrent AF during a 3-year follow-up period was determined and correlated with ablation technology and practices, antiarrhythmic medications, and patient comorbid conditions.
From 2011 to 2021, the cardiac electrophysiology lab adopted irrigated-contact force ablation catheters, high-power short duration ablation lesions, steady-pacing, jet ventilation, and eliminated stepwise linear ablation for AF ablation. During this time the number of first time AF ablations increased from 403 to 1074, the percentage of patients requiring repeat AF-related intervention within 3-years of the index procedure dropped from 22% to 14%, mean procedure time decreased from 271 ± 65 to 135 ± 36 min, and mean annual major adverse event rate remained constant at 1.1 ± 0.5%. Patient comorbid conditions increased during this time period and antiarrhythmic use was unchanged.
Rates of redo-AF ablation or DCCV following an initial AF ablation at a single center decreased 36% over a 10-year period. Procedural and technological changes likely contributed to this improvement, despite increased AF related comorbidities.
在过去的十年中,射频消融技术治疗心房颤动(AF)得到了迅速发展。我们研究了在一家主要学术医疗中心的十年期间,技术和程序的进步对手术时间和消融结果的影响。
从 2011 年至 2021 年,在纽约大学朗格尼健康中心(NYU Langone Health)首次接受 AF 消融术的患者中收集了临床数据。在 3 年的随访期间,确定了因复发性 AF 而再次进行 AF 消融术或直流电复律(DCCV)的时间,并将其与消融技术和实践、抗心律失常药物以及患者合并症相关联。
从 2011 年到 2021 年,心脏电生理实验室采用了灌流接触力消融导管、高功率短持续时间消融病灶、稳定起搏、射流通气,并消除了用于 AF 消融的逐步线性消融。在此期间,首次 AF 消融术的数量从 403 例增加到 1074 例,索引手术后 3 年内需要重复 AF 相关干预的患者比例从 22%下降到 14%,平均手术时间从 271±65 分钟减少到 135±36 分钟,而每年主要不良事件发生率保持不变,为 1.1±0.5%。在此期间,患者合并症增加,而抗心律失常药物的使用保持不变。
在单个中心,初始 AF 消融后再次进行 AF 消融术或 DCCV 的比率在十年内下降了 36%。尽管 AF 相关合并症增加,但程序和技术的变化可能促成了这一改善。