Blanchette Virginie, Armstrong David G, Drudi Laura, Rizzo Manfredi
Department of Human Kinetics and Podiatric Medicine, Université du Québec à Trois-Rivières, Trois-Rivières G8Z 4M3, Canada; VITAM - Sustainable Health Research Centre, Québec, Québec G1J 2G1, Canada; Centre de recherche du CISSS de Chaudière-Appalaches, Lévis G6V 3Z1, Canada.
Southwestern Academic Limb Salvage Alliance (SALSA), Department of Surgery, Keck School of Medicine of University of Southern California, Los Angeles, CA 90033, United States.
J Diabetes Complications. 2023 Mar;37(3):108407. doi: 10.1016/j.jdiacomp.2023.108407. Epub 2023 Jan 30.
This manuscript constitutes a commentary on: "Retrospective cohort study of long-term outcomes and prognostic factors for survival after lower extremity amputation in patients with diabetes" by Vuorlaakso et al. (2023). We aim to contribute to the reflection of their findings to support the comprehensive management of vulnerable individuals with multimorbidity and/frailty for limb preservation. There is an urgent need to understand the effects of frailty on overall survival after amputation, survival without major amputation, and the effect modification with multimorbidity.
本手稿是对Vuorlaakso等人(2023年)所著的《糖尿病患者下肢截肢术后长期结局及生存预后因素的回顾性队列研究》的评论。我们旨在对他们的研究结果进行反思,以支持对患有多种合并症和/或身体虚弱的弱势群体进行肢体保全的综合管理。迫切需要了解身体虚弱对截肢术后总体生存、无大截肢生存的影响,以及合并症对这种影响的修正作用。