Department of Diabetes and Endocrinology, Royal Melbourne Hospital, Parkville, Victoria, Australia.
Department of Medicine at Royal Melbourne Hospital, The University of Melbourne, Parkville, Victoria, Australia.
J Hosp Med. 2023 Apr;18(4):337-341. doi: 10.1002/jhm.13057. Epub 2023 Feb 4.
Admission to hospital provides an opportunity to optimize long-term diabetes management, but clinical inertia is common. We previously reported the randomized study of a proactive inpatient diabetes service (RAPIDS), investigating an early intervention model of care and demonstrated improved in-hospital glycemia and clinical outcomes. This follow-up study assessed whether proactive care in hospital improved postdischarge HbA1c. In a subgroup of 298 RAPIDS trial participants with type 2 diabetes, age <80 years, and admission HbA1c ≥ 7.0%, diabetes treatment intensification occurred more often in early intervention versus usual care groups (37% vs. 19% [p = .001]), adjusted odds ratio 3.2 (95% confidence interval [CI]: 1.7-6.0). There was a greater change in HbA1c in the early intervention group (mean -0.9% [95% CI -1.3 to -0.4]) versus the usual care group (-0.3% [-0.6 to -0.1]), p = .029. The value of acute care by dedicated inpatient diabetes teams can extend beyond improving inpatient clinical outcomes and can lead to sustained improvement in glycemia.
住院为优化长期糖尿病管理提供了机会,但临床惰性很常见。我们之前报道了一项主动的住院糖尿病服务(RAPIDS)的随机研究,该研究调查了一种早期干预护理模式,并证明了改善住院期间血糖和临床结局。这项随访研究评估了住院期间的主动护理是否改善了出院后 HbA1c。在 RAPIDS 试验中,有 298 名年龄<80 岁且入院时 HbA1c≥7.0%的 2 型糖尿病亚组参与者中,早期干预组的糖尿病治疗强化程度高于常规护理组(37%比 19%[p=0.001]),调整后的优势比为 3.2(95%置信区间[CI]:1.7-6.0)。早期干预组的 HbA1c 变化更大(平均-0.9%[95%CI-1.3 至-0.4]),而常规护理组的 HbA1c 变化更小(-0.3%[-0.6 至-0.1]),p=0.029。专门的住院糖尿病团队提供的急性护理的价值不仅可以改善住院期间的临床结局,还可以持续改善血糖水平。