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评估刚果民主共和国姆布吉马伊地区转诊医院的外科抗生素预防实践。

Evaluation of the practice of surgical antibiotic prophylaxis in a Zonal Referral Hospital in Mbujimayi, Democratic Republic of the Congo (DRC).

机构信息

Department of Surgery, Université Officielle de Mbujimayi (UOM), Mbujimayi, Democratic Republic of the Congo.

Department of Surgery, Muhimbili University of Health and Allied Sciences (MUHAS), Dar es Salaam, United Republic of Tanzania.

出版信息

BMC Surg. 2023 Feb 4;23(1):28. doi: 10.1186/s12893-023-01926-7.

Abstract

BACKGROUND

Surgical Antibiotic Prophylaxis (SAP) is helpful in preventing patients from developing Surgical Site Infections (SSI). In Mbujimayi, the documentation on the practice of SAP is outdated and inadequate. The last study was conducted more than 5 years ago. This study aims at assessing the compliance of the practice of antibiotic prophylaxis in the surgical and obstetrics-gynecology departments of the Bonzola Zonal Referral Hospital (BZRH) compared to the international standards.

METHODS

A prospective observational study was conducted from March 2020 to March 2021 involving 324 surgical patients who received antibiotic prophylaxis. Interventions were assessed as "compliant" if all the variables individually complied with the criteria for antibiotic prophylaxis use.

RESULTS

Three hundred and twenty-four patients were enrolled in this study. Compliance was found to be 87.35% for the indication for administration; 0.31% for the choice of the molecule; 3.65% for the time of the first administration; none for the duration of antibiotic prophylaxis. Therefore, the overall compliance was nil. This study shows a significant gap when the current practice in Mbujimayi town is compared to the recommendations of international societies.

CONCLUSION

SAP is often indicated in accordance with international recommendations in Mbujimayi. However, the choice of the molecule, the dosage, the time of first administration and the duration of SAP deviate from them. Thus, the compliance of SAP is nil.

摘要

背景

外科抗生素预防(Surgical Antibiotic Prophylaxis,SAP)有助于预防患者发生手术部位感染(Surgical Site Infections,SSI)。在姆布吉马伊,关于 SAP 实践的文件已经过时且不充分。最后一次研究是在 5 年多前进行的。本研究旨在评估 Bonzola 区域转诊医院(BZRH)外科和妇产科部门 SAP 实践的依从性与国际标准相比。

方法

本研究为 2020 年 3 月至 2021 年 3 月进行的一项前瞻性观察研究,共纳入 324 名接受抗生素预防的外科患者。如果所有变量均单独符合抗生素预防使用标准,则将干预措施评估为“符合”。

结果

本研究共纳入 324 例患者。给药指征的符合率为 87.35%;分子选择的符合率为 0.31%;首次给药时间的符合率为 3.65%;抗生素预防持续时间的符合率为 0%。因此,总体符合率为零。与国际社会的建议相比,姆布吉马伊镇目前的实践存在显著差距。

结论

SAP 通常根据国际建议在姆布吉马伊进行指示。然而,分子的选择、剂量、首次给药时间和 SAP 的持续时间与这些建议不符。因此,SAP 的符合率为零。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d4fc/9899390/1732c6a58d1e/12893_2023_1926_Fig1_HTML.jpg

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