Panduro-Correa Vicky, Gomez-Gonzales Walter, Rabaan Ali A, Valencia-Martínez Juan Carlos, Gutiérrez-Acuña Yeni, Chihuantito-Abal Luis, Zavaleta-Oliver Jenny, Barboza Joshuan J, Rodriguez-Morales Alfonso J, Arteaga-Livias Kovy
Facultad de Medicina, Universidad Nacional Hermilio Valdizán. Huánuco, Peru.
Escuela de Medicina Humana. Universidad Privada San Juan Bautista, Lima, Perú.
Infez Med. 2023 Sep 1;31(3):364-373. doi: 10.53854/liim-3103-10. eCollection 2023.
Surgical site infections (SSIs) can increase mortality and morbidity in patients after surgery. Antibiotic prophylaxis is an effective measure to prevent SSIs, but inappropriate prescription is frequent. The objective of the study was to determine compliance with the clinical practice guideline for antibiotic prophylaxis in the general surgery and gynecology and obstetrics wards in the city of Huánuco, Peru.
An analytical cross-sectional study was carried out on all surgical interventions in the general surgery and gynecology and obstetrics services during the year 2019. Compliance was determined based on the chosen antibiotic, dose, time of administration, and duration of prophylaxis. Related factors considered were age, presence of co-morbidities, surgery performed, duration of surgery, types of procedure, anesthesia, as well as years as a surgeon and anesthesiologist.
A total of 557 medical records of patients with a median age of 33 years undergoing surgery were collected,. Antibiotic prophylaxis was correctly followed in all aspects in 14.6% of cases in the general surgery service and only in 5.6% of cases in the gynecology and obstetrics service. The correct duration of prophylaxis was 11.6% and 19.7% in general surgery and gynecology and obstetrics, respectively.
Low compliance with institutional clinical practice guidelines for antibiotic prophylaxis was identified in both services. However, surgical interventions in the general surgery service presented better compliance with antibiotic prophylaxis compared to gynecology and obstetrics procedures.
手术部位感染（SSIs）会增加术后患者的死亡率和发病率。抗生素预防是预防手术部位感染的有效措施，但不合理用药情况屡见不鲜。本研究的目的是确定秘鲁瓦努科市普通外科以及妇产科病房中抗生素预防的临床实践指南的依从性。
对2019年普通外科以及妇产科服务中的所有手术干预进行了一项分析性横断面研究。根据所选抗生素、剂量、给药时间以及预防持续时间来确定依从性。所考虑的相关因素包括年龄、合并症的存在、所进行的手术、手术持续时间、手术类型、麻醉方式，以及外科医生和麻醉医生的工作年限。
总共收集了557例接受手术患者的病历，患者中位年龄为33岁。普通外科服务中14.6%的病例在各方面均正确遵循了抗生素预防措施，而妇产科服务中仅5.6%的病例做到了这一点。普通外科和妇产科预防措施的正确持续时间分别为11.6%和19.7%。
两项服务中抗生素预防的机构临床实践指南依从性均较低。然而，与妇产科手术相比，普通外科服务中的手术干预在抗生素预防方面的依从性更好。
