Salazar-Ciudad Isaac, Cano-Fernández Hugo
Centre de Recerca Matemàtica, Cerdanyola del Vallès, Spain.
Genomics, Bioinformatics and Evolution, Departament de Genètica i Microbiologia, Universitat Autònoma de Barcelona, Barcelona, Spain.
Bioessays. 2023 Mar;45(3):e2200205. doi: 10.1002/bies.202200205. Epub 2023 Feb 5.
A foundational idea of evo-devo is that morphological variation is not isotropic, that is, it does not occur in all directions. Instead, some directions of morphological variation are more likely than others from DNA-level variation and these largely depend on development. We argue that this evo-devo perspective should apply not only to morphology but to evolution at all phenotypic levels. At other phenotypic levels there is no development, but there are processes that can be seen, in analogy to development, as constructing the phenotype (e.g., protein folding, learning for behavior, etc.). We argue that to explain the direction of evolution two types of arguments need to be combined: generative arguments about which phenotypic variation arises in each generation and selective arguments about which of it passes to the next generation. We explain how a full consideration of the two types of arguments improves the explanatory power of evolutionary theory. Also see the video abstract here: https://youtu.be/Egbvma_uaKc.
演化发育生物学的一个基本观点是，形态变异并非各向同性，也就是说，它并非在所有方向上都发生。相反，从DNA水平的变异来看，形态变异的某些方向比其他方向更有可能出现，而这些很大程度上取决于发育过程。我们认为，这种演化发育生物学的观点不仅应适用于形态，还应适用于所有表型水平的进化。在其他表型水平上不存在发育过程，但存在一些过程，类似于发育过程，可以看作是构建表型（例如蛋白质折叠、行为学习等）。我们认为，为了解释进化的方向，需要将两种类型的论点结合起来：关于每一代中出现哪些表型变异的生成性论点，以及关于其中哪些会传递到下一代的选择性论点。我们解释了全面考虑这两种类型的论点如何提高进化理论的解释力。另请参阅此处的视频摘要：https://youtu.be/Egbvma_uaKc 。
