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印度的结核病负担及其在 1990 年至 2019 年期间的控制情况:来自 2019 年全球疾病负担研究的证据。

Tuberculosis burden in India and its control from 1990 to 2019: Evidence from global burden of disease study 2019.

机构信息

Department of Community Medicine, Dr Baba Saheb Ambedkar Medical College and Hospital, Sector-6, Rohini, Delhi, 110085, India.

Doctors for You (NGO), Delhi, 110048, India.

出版信息

Indian J Tuberc. 2023 Jan;70(1):87-98. doi: 10.1016/j.ijtb.2022.03.016. Epub 2022 Mar 15.

Abstract

BACKGROUND

Tuberculosis is still a major public health problem in India. This study aims to assess trends in the burden of tuberculosis from 1990 to 2019 for tracking success of tuberculosis control programme in India.

METHODS

In this study, the 2019 global burden of disease study data were used to measure the incidence, prevalence, mortality, and disability-adjusted life years lost (DALY)rates of Tuberculosis during 1990-2019 for India and its states. Age and gender-specific rates were also analyzed for India. All rates were age-standardized and 95% uncertainty intervals (UIs) were computed.

RESULT

Overall incidence, prevalence, death and DALY of TB decreased in India from 1990 to 2019. Tuberculosis morbidity and mortality was higher in males as compared to females. Incidence of TB was low in children up to 14 years of age. Prevalence of TB was higher in females as compared to males till 29 years of age, whereas higher prevalence was reported in males as compared to females in adults aged 30 years and more. Death rate of TB was low in children and young adults up to 29 years of age.

CONCLUSION

This study shows that overall incidence, prevalence, death and DALY of tuberculosis decreased from 1990 to 2019 in India. The burden of TB was higher among males as compared to females during study period. TB affects all the age groups but deaths were higher in older age groups.

摘要

背景

结核病仍然是印度的一个主要公共卫生问题。本研究旨在评估 1990 年至 2019 年结核病负担的趋势,以跟踪印度结核病控制规划的成功。

方法

本研究使用 2019 年全球疾病负担研究数据,衡量印度及其各邦在 1990-2019 年期间结核病的发病率、患病率、死亡率和伤残调整生命年(DALY)率。还分析了印度的年龄和性别特异性发病率。所有发病率均进行了年龄标准化,并计算了 95%的置信区间(UI)。

结果

1990 年至 2019 年,印度的结核病总发病率、患病率、死亡率和 DALY 均有所下降。与女性相比,男性的结核病发病率和死亡率更高。14 岁以下儿童的结核病发病率较低。与男性相比,女性的结核病患病率在 29 岁之前更高,而在 30 岁及以上的成年人中,男性的结核病患病率则高于女性。结核病死亡率在 29 岁以下的儿童和青年中较低。

结论

本研究表明,1990 年至 2019 年,印度的结核病总发病率、患病率、死亡率和 DALY 均有所下降。在研究期间,男性的结核病负担高于女性。结核病影响所有年龄组,但死亡人数在老年组更高。

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