塞尔维亚的结核病负担

Burden of tuberculosis in Serbia.

作者信息

Gledovic Zorana, Vlajinac Hristina, Pekmezovic Tatjana, Grujicic-Sipetic Sandra, Grgurevic Anita, Pesut Dragica

机构信息

Institute of Epidemiology, School of Medicine, University of Belgrade, Visegrdska 26A, Belgrade 11000, Serbia.

出版信息

Am J Infect Control. 2006 Dec;34(10):676-9. doi: 10.1016/j.ajic.2006.03.013.

DOI:10.1016/j.ajic.2006.03.013

PMID:17161745

Abstract

The objective of this study is to estimate the burden of tuberculosis (TB) in Serbia in the period 1992-2002 based on incidence, mortality, and disability adjusted life years (DALY). The average age-adjusted TB incidence rate in the period 1992-2002 was 36.7/100,000 in males and 21.4/100,000 in females. During the period observed, TB incidence levelled of after a long period of decreasing trend during the preceding several decades. The incidence showed slightly increasing tendency in males and decreasing one in females. The average age-adjusted mortality rate was 4.1/100,000 in males and 1.3/100,000 in females. Mortality rates significantly decreased in both males (P = .0001) and females (P = .0001). The burden of TB (DALY) was 0.70/1000 for males and 0.26/1000 for females. DALY rates significantly decreased in both males (P = .009) and females (P = .008). TB incidence and mortality as well as DALY rates increased with aging.

摘要

本研究的目的是基于发病率、死亡率和伤残调整生命年（DALY）来估算1992 - 2002年期间塞尔维亚的结核病负担。1992 - 2002年期间，年龄调整后的结核病平均发病率男性为36.7/10万，女性为21.4/10万。在观察期内，结核病发病率在之前几十年长期下降趋势后趋于平稳。发病率在男性中呈略微上升趋势，在女性中呈下降趋势。年龄调整后的平均死亡率男性为4.1/10万，女性为1.3/10万。男性和女性的死亡率均显著下降（男性P = 0.0001，女性P = 0.0001）。结核病负担（DALY）男性为0.70/1000，女性为0.26/1000。男性和女性的DALY率均显著下降（男性P = 0.009，女性P = 0.008）。结核病发病率、死亡率以及DALY率均随年龄增长而上升。