Epidemic Intelligence Service, Division of Scientific Education and Professional Development, Centers for Disease Control and Prevention, Atlanta, Georgia; Department of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, California.
Department of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, California.
Womens Health Issues. 2023 May-Jun;33(3):280-288. doi: 10.1016/j.whi.2023.01.001. Epub 2023 Feb 3.
The study's objectives were to examine rates of severe maternal morbidity (SMM) over a 10-year period and assess racial/ethnic disparities in SMM among insured women in a large, integrated health care system in Southern California.
We included Kaiser Permanente Southern California (KPSC) health plan members who gave birth at ≥20 weeks' gestation in a KPSC-owned hospital during 2008-2017. An SMM case was defined as presence of one or more indicators of an SMM event during a birth hospitalization, identified using maternal electronic health records. Crude SMM rates/10,000 births were calculated by year and maternal race/ethnicity. Modified Poisson regression models were used to assess the association between race/ethnicity and SMM adjusted for other maternal demographics, pregnancy characteristics, and preexisting conditions.
We identified 5,915 SMM cases among 335,310 births. Crude SMM rates increased from 94.7 per 10,000 in 2008 to 192.6 in 2015 and 249.5 in 2017. Non-Hispanic Black (adjusted risk ratio [aRR] 1.52; 95% confidence interval [CI] 1.37-1.69), Asian/Pacific Islander (aRR 1.29, 95% CI 1.18-1.41), and Hispanic (aRR 1.18, 95% CI 1.10-1.27) women had greater likelihood of SMM than non-Hispanic White women. After further adjusting for preexisting health conditions, differences in SMM by race/ethnicity remained.
SMM rates increased during 2008-2017 and women of racial and ethnic minority groups, particularly non-Hispanic Black women, were more likely to experience an SMM event than non-Hispanic White women. Multilevel approaches to understanding structural and social factors that may be associated with racial and ethnic disparities in SMM are needed to develop and test effective interventions to reduce SMM.
本研究旨在考察 10 年间严重产妇发病率(SMM)的发生率,并评估在加利福尼亚州南部一个大型综合医疗保健系统中,参保妇女的 SMM 发生率存在的种族/民族差异。
我们纳入了在 2008 年至 2017 年期间在 Kaiser Permanente Southern California(KPSC)所有医院分娩且孕周≥20 周的 KPSC 健康计划成员。通过产妇电子健康记录,使用一个或多个 SMM 事件指标来定义 SMM 病例。按年份和产妇的种族/民族计算每 10000 例分娩的粗 SMM 发生率。采用修正泊松回归模型,在校正其他产妇人口统计学、妊娠特征和既往疾病等因素后,评估种族/民族与 SMM 之间的关联。
我们在 335310 例分娩中发现了 5915 例 SMM 病例。2008 年粗 SMM 发生率为 94.7/10000,到 2015 年增至 192.6/10000,到 2017 年进一步增至 249.5/10000。非西班牙裔黑人(调整风险比[aRR] 1.52;95%置信区间[CI] 1.37-1.69)、亚裔/太平洋岛民(aRR 1.29,95%CI 1.18-1.41)和西班牙裔(aRR 1.18,95%CI 1.10-1.27)女性发生 SMM 的可能性大于非西班牙裔白人女性。进一步调整既往健康状况后,种族/民族间的 SMM 差异仍然存在。
2008 年至 2017 年期间,SMM 发生率增加,非裔和少数族裔女性,尤其是非西班牙裔黑人女性,发生 SMM 的可能性大于非西班牙裔白人女性。需要采用多层次方法来了解可能与 SMM 种族/民族差异相关的结构性和社会因素,以制定和测试减少 SMM 的有效干预措施。