Razafindrasoa Zamelina Angela, Razafimpihanina Sonia Marcelle, Rasoafaranirina Marie Odette, Martin Fidy Arnauld, Andriamahenina Finaritra Princy Parfait, Andriarimanga Diamondra Ombanjanahary, Rakotomizao Jocelyn Robert, Tiaray Harison Michel, Rakotoson Joëlson Lovaniaina, Raharimanana Rondro Nirina
Centre Hospitalier Universitaire Fenoarivo, Antananarivo, Madagascar.
Centre Hospitalier Universitaire Tambohobe, Fianarantsoa, Madagascar.
Egypt J Intern Med. 2023;35(1):9. doi: 10.1186/s43162-023-00192-6. Epub 2023 Jan 31.
Since its discovery, COVID-19 has often been the first diagnosis of dyspnea and asthenia, especially during the pandemic waves. However, it is not always COVID-19. We report a particular case of a late-diagnosed HIV-positive patient in Madagascar.
A 21-year-old male patient was admitted to a hospital center in Antananarivo for dyspnea and poor general condition. Physical examination revealed hypoxemia of 85% on room air. His chest X-ray showed bilateral reticular-micronodular opacities. He was suspected and treated for COVID-19. On the 15th day of hospitalization, HIV-1 infection complicated by probable pneumocystis was diagnosed. On the other hand, a multimetastatic testicular cancer was also suspected. The patient died after a few hours of hospitalization in the intensive care unit.
This was a case of an HIV-positive patient belatedly diagnosed in the complications stage during the COVID-19 pandemic wave. The investigation of the differential diagnoses remains crucial to avoid serial misdiagnosis and to adjust therapeutic management.
自发现以来,新型冠状病毒肺炎(COVID-19)常常是呼吸困难和乏力的首要诊断病因,尤其是在疫情高峰期。然而,病因并不总是COVID-19。我们报告了马达加斯加一名确诊较晚的HIV阳性患者的特殊病例。
一名21岁男性患者因呼吸困难和身体状况不佳入住塔那那利佛的一家医院中心。体格检查显示在室内空气中血氧饱和度为85%。他的胸部X光显示双侧网状微小结节状混浊。他被怀疑感染了COVID-19并接受治疗。住院第15天,诊断出HIV-1感染并发可能的肺孢子菌病。另一方面,还怀疑有多发性转移性睾丸癌。该患者在重症监护病房住院数小时后死亡。
这是一例在COVID-19疫情高峰期并发症阶段才被确诊的HIV阳性患者。鉴别诊断的调查对于避免连续误诊和调整治疗管理仍然至关重要。