Atram Manisha A, Shivkumar V B, Gangane Nitin M
Department of Pathology, Mahatma Gandhi Institute of Medical Sciences, Sewagram, Wardha, Maharashtra 442102 India.
Mahatma Gandhi Institute of Medical Sciences, Sewagram, Wardha, Maharashtra 442102 India.
Indian J Otolaryngol Head Neck Surg. 2022 Dec;74(Suppl 3):5949-5953. doi: 10.1007/s12070-021-02594-w. Epub 2021 May 7.
Adenoid cystic carcinoma is rare, locally aggressive salivary gland tumor. It has indolent course, multiple local recurrences and delayed distant metastasis in lung, bone, liver and soft tissues which are detected up to a maximum of 5.5 years after local-regional resection of the primary tumor. Intracranial remote metastasis of ACCs is extremely rare, and very few cases have been reported in the literature. Here we report a rare case of intracranial remote metastasis of ACC of the parotid gland developed after 15 years of primary curative surgery, emphasizing long term follow up on these cases.
腺样囊性癌是一种罕见的、具有局部侵袭性的涎腺肿瘤。其病程进展缓慢，易多次局部复发，并出现延迟性远处转移，转移部位包括肺、骨、肝和软组织，在原发肿瘤局部区域切除后最长可达5.5年才被发现。腺样囊性癌的颅内远处转移极为罕见，文献报道的病例很少。在此，我们报告一例腮腺腺样囊性癌在根治性手术后15年发生颅内远处转移的罕见病例，强调对这些病例进行长期随访。
