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头颈部手术后乳糜漏的管理;我们在52例病例中的成功经验及文献综述

Management of Chyle Leak After Head and Neck Surgery; Our Meritorious Experience in 52 Cases and Review of Literature.

作者信息

Nandy Kunal, Jayaprakash Dipin, Rai Shreya, Kumar Ajay, Puj Ketul, Tripathi Umank

机构信息

Department of Surgical Oncology, Gujarat Cancer and Research Institute, Asarwa, Ahmedabad, Gujarat 380016 India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2022 Dec;74(Suppl 3):5978-5983. doi: 10.1007/s12070-021-02648-z. Epub 2021 May 24.

Abstract

Iatrogenic chyle leak is commonly seen when dissection happens very low in neck. Management of chyle leak is conservative with compression dressing, fat restricted diet, somatostatin analogues. Surgery is required in extreme cases with failure of conservative treatment. This is a retrospective observational study carried out from a prospectively maintained database. A total of 6482 head and neck surgeries with neck dissections were carried out between January 2015 till July 2020 at our tertiary cancer center. Out of which there were 52 cases of chyle leak reported post neck dissection. All details regarding age, sex, primary tumor location, surgery performed, level of nodal dissection performed, details related to chyle leak from beginning day and its progression and management offered. The median age in the study group was 42 years (24-70 years). Chyle leak was most commonly seen on left side (88.5%). Low output leaks( = 43) resolved within a median period of 9 days (5-13 days) period of conservative management. High output leak ( = 9) had leak resolution within a median period of 12 days (7-19 days). Patients who had received preoperative radiotherapy and who had extra nodal extension in lymph nodes had significantly higher incidence of high output leaks. Chyle leak is a rare but serious complication in head and neck surgery. Timely identification and management is crucial. Conservative management is mainstay. Surgical management is instituted in cases of failure of conservative management.

摘要

医源性乳糜漏常见于颈部极低位置的解剖操作时。乳糜漏的治疗采用保守方法,包括加压包扎、低脂饮食、使用生长抑素类似物。在保守治疗失败的极端情况下才需要进行手术。这是一项基于前瞻性维护数据库进行的回顾性观察研究。2015年1月至2020年7月期间,我们的三级癌症中心共进行了6482例头颈部手术并伴有颈部清扫术。其中,有52例患者在颈部清扫术后报告发生乳糜漏。记录了所有关于年龄、性别、原发肿瘤位置、所进行的手术、所进行的淋巴结清扫水平、从乳糜漏开始之日起的详细情况及其进展和所采取的治疗措施。研究组的中位年龄为42岁(24 - 70岁)。乳糜漏最常见于左侧(88.5%)。低流量漏出(n = 43)在保守治疗的中位9天(5 - 13天)内得到解决。高流量漏出(n = 9)在中位12天(7 - 19天)内漏出得到解决。接受过术前放疗以及淋巴结有结外扩展的患者高流量漏出的发生率显著更高。乳糜漏是头颈部手术中一种罕见但严重的并发症。及时识别和处理至关重要。保守治疗是主要方法。在保守治疗失败的情况下采用手术治疗。

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