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显微外科中央淋巴重建——不同解剖层面胸导管淋巴静脉吻合术的作用

Microsurgical central lymphatic reconstruction-the role of thoracic duct lymphovenous anastomoses at different anatomical levels.

作者信息

Weinzierl Andrea, Grünherz Lisanne, Puippe Gilbert Dominique, Gnannt Ralph, von Reibnitz Donata, Giovanoli Pietro, Vetter Diana, Möhrlen Ueli, Wildgruber Moritz, Müller Andreas, Pieper Claus Christian, Gutschow Christian Alexander, Lindenblatt Nicole

机构信息

Department of Plastic Surgery and Hand Surgery, University Hospital Zurich (USZ), Zurich, Switzerland.

Institute of Diagnostic and Interventional Radiology, University Hospital Zurich (USZ), Zurich, Switzerland.

出版信息

Front Surg. 2024 May 17;11:1415010. doi: 10.3389/fsurg.2024.1415010. eCollection 2024.

Abstract

INTRODUCTION

In recent years advances have been made in the microsurgical treatment of congenital or acquired central lymphatic lesions. While acquired lesions can result from any surgery or trauma of the central lymphatic system, congenital lymphatic lesions can have a variety of manifestations, ranging from singular thoracic duct abnormalities to complex multifocal malformations. Both conditions may cause recurrent chylous effusions and downstream lymphatic congestion depending on the anatomical location of the thoracic duct lesion and are associated with an increased mortality due to the permanent loss of protein and fluid.

METHODS

We present a case series of eleven patients undergoing central lymphatic reconstruction, consisting of one patient with a cervical iatrogenic thoracic duct lesion and eleven patients with different congenital thoracic duct lesions or thrombotic occlusions.

RESULTS

Anastomosis of the thoracic duct and a nearby vein was performed on different anatomical levels depending on the underlying central lymphatic pathology. Cervical ( = 4), thoracic ( = 1) or abdominal access ( = 5) was used for central lymphatic reconstruction with promising results. In 9 patients a postoperative benefit with varying degrees of symptom regression was reported.

CONCLUSION

The presented case series illustrates the current rapid advances in the field of central microsurgical reconstruction of lymphatic lesions alongside the relevant literature.

摘要

引言

近年来,先天性或后天性中枢淋巴系统病变的显微外科治疗取得了进展。后天性病变可由中枢淋巴系统的任何手术或创伤引起,而先天性淋巴病变可有多种表现,从单一的胸导管异常到复杂的多灶性畸形。这两种情况都可能根据胸导管病变的解剖位置导致反复乳糜性积液和下游淋巴充血,并因蛋白质和液体的永久性丧失而导致死亡率增加。

方法

我们展示了一组11例接受中枢淋巴重建的患者病例系列,其中包括1例患有颈源性医源性胸导管病变的患者和11例患有不同先天性胸导管病变或血栓闭塞的患者。

结果

根据潜在的中枢淋巴病理情况,在不同的解剖层面进行胸导管与附近静脉的吻合。采用颈部(=4)、胸部(=1)或腹部入路(=5)进行中枢淋巴重建,效果良好。9例患者报告术后有不同程度症状缓解的益处。

结论

本病例系列说明了淋巴病变中枢显微外科重建领域目前的快速进展以及相关文献情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2915/11140048/2e41d26eae86/fsurg-11-1415010-g001.jpg

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