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更年期及其对嗓音的影响。

Menopause and its Effect on Voice.

作者信息

Shankar Ravi, Raj Anoop, Rathore Praveen Kumar, Meher Ravi, Kaushik Smita, Batra Vasun

机构信息

Department of Head and Neck Surgery, Tata Memorial Hospital, Parel, Mumbai, Maharashtra India.

ENT and Head and Neck Surgery, Sharda Hospital, Greater Noida, Delhi NCR, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2022 Dec;74(Suppl 3):5524-5530. doi: 10.1007/s12070-021-02870-9. Epub 2021 Sep 21.

Abstract

ABSTRACT

This study was designed to study the impact of menopause on voice quality. Cross-sectional Observational study with a total of 100 subjects. All subjects underwent biochemical analysis which included thyroid function tests, estrogen levels, progesterone levels and underwent voice analysis using the VAUGHMI voice analyser software. 50 postmenopausal females as cases and 50 premenopausal females as controls were taken for the study. The females were of the age group 35-55 yrs in order to remove age as confounding factor. The primary outcome measure was Total score, calculated based on harshness, hoarseness and breathiness. The postmenopausal females had a poorer voice quality than the premenopausal females (Total score 1.62 vs 2.48,  < 0.001). There was a significant difference between the fundamental frequency and pitch and perturbation in frequency of the postmenopausal females as compared to premenopausal females. The difference in the perturbation in the intensity of the voice was not significant. No linear correlation could be established between the voice quality and oestrogen or progesterone levels but the intergroup variation of the two parameters was significant. The premenopausal females have better voice quality than postmenopausal females. The relationship between hormonal level and voice quality couldn't be established. Further studies are required to assess the relation of hormone levels & voice quality with the possibility of exploring voice cosmesis.

LEVEL OF EVIDENCE

Level 3.

摘要

摘要

本研究旨在探讨绝经对嗓音质量的影响。采用横断面观察性研究,共纳入100名受试者。所有受试者均接受了生化分析,包括甲状腺功能测试、雌激素水平、孕激素水平,并使用VAUGHMI嗓音分析仪软件进行嗓音分析。选取50名绝经后女性作为病例组,50名绝经前女性作为对照组进行研究。为排除年龄作为混杂因素,女性年龄在35 - 55岁之间。主要观察指标为总分,根据粗糙感、嘶哑感和呼吸音计算得出。绝经后女性的嗓音质量比绝经前女性差(总分1.62对2.48,<0.001)。与绝经前女性相比,绝经后女性的基频、音高和频率微扰存在显著差异。嗓音强度微扰的差异不显著。嗓音质量与雌激素或孕激素水平之间未建立线性相关性,但这两个参数的组间差异显著。绝经前女性的嗓音质量优于绝经后女性。激素水平与嗓音质量之间的关系尚未明确。需要进一步研究评估激素水平与嗓音质量的关系,并探讨嗓音美容的可能性。

证据水平

3级。

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