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古吉拉特邦一家区级医院对印度糖尿病风险评分和随机血糖检测用于2型糖尿病患者机会性筛查的评估。

Evaluation of Indian Diabetes Risk Score and Random Blood Sugar Testing for Opportunistic Screening of Type 2 Diabetes Patients at a District Hospital of Gujarat.

作者信息

Fichadiya Nilesh Chandrakant, Kadri Ammiruddin M, Dave Bhargav B

机构信息

Department of Community Medicine, P. D. U. Medical College, Rajkot, Gujarat, India.

State Health System Resource Centre, Gujarat, India.

出版信息

Indian J Community Med. 2022 Oct-Dec;47(4):517-521. doi: 10.4103/ijcm.ijcm_1390_21. Epub 2022 Dec 14.

Abstract

BACKGROUND

India is home to 69.2 million diabetics. For opportunistic screening of type 2 diabetes mellitus (DM), random capillary blood sugar (RBS) testing is used. Another method is Indian Diabetes Risk Score (IDRS), which is a simple and cost effective method for opportunistic screening of type 2 DM patients. The aim is to evaluate the screening test parameters of RBS testing and IDRS for opportunistic screening of undiagnosed type 2 DM patients.

MATERIALS AND METHODS

A cross-sectional study was done during February 2017 to August 2017 at a district hospital of Western Gujarat. A sample size of 317 patients was calculated using Buderer's formula. Systematic random sampling was used and every third patient was selected from the general Outpatient Department(OPD) attendees of 30 years or more. MS Excel and Epi Info v7.2 was used for statistical analysis. Screening parameters and accuracy of IDRS and RBS were calculated taking result of the oral glucose tolerance test as clinical reference.

RESULTS

The mean age of study participants was 50.9 (SD 12.17) years with 44.2% males and 55.8% females. Sensitivity and specificity of RBS was 72.4% and 69.1%. Sensitivity and specificity of IDRS was 93.1% and 29.0%. On simultaneous (parallel) screening by IDRS and RBS, sensitivity was 98.3% and specificity was 23.2%. In sequential screening, where IDRS was used followed by RBS, sensitivity was 67.2% and specificity was 74.9%.

CONCLUSIONS

This study has found that sequential screening using a simple diabetes risk score like IDRS followed by RBS is having higher accuracy and reduced cost of opportunistic screening of type 2 diabetes. Adopting sequential screening using IDRS as first step of screening followed by RBS in those found as high risk by IDRS is recommended.

摘要

背景

印度有6920万糖尿病患者。为了对2型糖尿病(DM)进行机会性筛查,采用随机毛细血管血糖(RBS)检测。另一种方法是印度糖尿病风险评分(IDRS),这是一种用于2型糖尿病患者机会性筛查的简单且经济有效的方法。目的是评估RBS检测和IDRS用于未诊断的2型糖尿病患者机会性筛查的检测参数。

材料与方法

2017年2月至2017年8月在古吉拉特邦西部的一家区级医院进行了一项横断面研究。使用布德勒公式计算出317名患者的样本量。采用系统随机抽样,从30岁及以上普通门诊(OPD)就诊者中每隔第三位患者进行选择。使用MS Excel和Epi Info v7.2进行统计分析。以口服葡萄糖耐量试验结果作为临床参考,计算IDRS和RBS的筛查参数及准确性。

结果

研究参与者的平均年龄为50.9(标准差12.17)岁,男性占44.2%,女性占55.8%。RBS的敏感性和特异性分别为72.4%和69.1%。IDRS的敏感性和特异性分别为93.1%和29.0%。通过IDRS和RBS同时(平行)筛查时,敏感性为98.3%,特异性为23.2%。在序贯筛查中,先使用IDRS再使用RBS,敏感性为67.2%,特异性为74.9%。

结论

本研究发现,像IDRS这样的简单糖尿病风险评分先进行序贯筛查,然后进行RBS,在2型糖尿病机会性筛查中具有更高的准确性且降低了成本。建议采用以IDRS作为筛查第一步,然后对IDRS发现的高风险者进行RBS的序贯筛查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a836/9891056/788e2c574656/IJCM-47-517-g001.jpg

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