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一名患有难治性特发性血小板减少性紫癜男性患者的复发性脑梗死和多血管血栓形成：病例报告

Recurrent Cerebral Infarctions and Multi-Vessel Thrombosis in a Male Patient with Refractory Idiopathic Thrombocytopenic Purpura: a Case Report.

作者信息

Lee Jong Weon, Kim Hyoung Seop

机构信息

Department of Physical Medicine and Rehabilitation, National Health Insurance Service Ilsan Hospital, Goyang, Korea.

出版信息

Brain Neurorehabil. 2021 Mar 18;14(2):e18. doi: 10.12786/bn.2021.14.e18. eCollection 2021 Jul.

DOI:10.12786/bn.2021.14.e18
PMID:36743435
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9879500/
Abstract

Idiopathic thrombocytopenic purpura (ITP) mostly presents with bleeding tendencies, and thrombotic events are very uncommon. Our case report presents a male patient with ITP refractory to standardized therapies who continuously showed thrombocytopenia and hematuria. With no evidence of autoimmune diseases or other secondary causes of ITP, he developed recurrent cerebral infarctions and deep venous thrombosis. Our report calls for attention to possible thrombotic events, as well as more common bleeding tendencies in patients with ITP and outlines rehabilitation treatment specially designed for ITP patients with rare thrombotic complications.

摘要

特发性血小板减少性紫癜（ITP）大多表现为出血倾向，血栓形成事件非常罕见。我们的病例报告介绍了一名对标准化治疗无效的ITP男性患者，该患者持续出现血小板减少和血尿。在没有自身免疫性疾病或ITP其他继发原因的证据的情况下，他发生了复发性脑梗死和深静脉血栓形成。我们的报告呼吁关注ITP患者可能出现的血栓形成事件以及更常见的出血倾向，并概述了专门为患有罕见血栓形成并发症的ITP患者设计的康复治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b25d/9879500/8991966616c1/bn-14-e18-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b25d/9879500/31d6f0da9f94/bn-14-e18-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b25d/9879500/a1fc57fffc8c/bn-14-e18-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b25d/9879500/8991966616c1/bn-14-e18-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b25d/9879500/31d6f0da9f94/bn-14-e18-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b25d/9879500/a1fc57fffc8c/bn-14-e18-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b25d/9879500/8991966616c1/bn-14-e18-g003.jpg

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本文引用的文献

1
Clinical Practice Guideline for Stroke Rehabilitation in Korea-Part 1: Rehabilitation for Motor Function (2022).《韩国脑卒中康复临床实践指南 - 第1部分：运动功能康复（2022年）》
Brain Neurorehabil. 2023 Jul 17;16(2):e18. doi: 10.12786/bn.2023.16.e18. eCollection 2023 Jul.
2
WFH Guidelines for the Management of Hemophilia, 3rd edition.《血友病管理的居家指南》第三版
Haemophilia. 2020 Aug;26 Suppl 6:1-158. doi: 10.1111/hae.14046. Epub 2020 Aug 3.
3
Epidemiology and Clinical Manifestations of Immune Thrombocytopenia.免疫性血小板减少症的流行病学和临床表现。
Hamostaseologie. 2019 Aug;39(3):238-249. doi: 10.1055/s-0039-1683416. Epub 2019 Mar 13.
4
Current practice and future directions in the diagnosis and acute treatment of ischaemic stroke.目前缺血性脑卒中的诊断和急性治疗的现状及未来方向。
Lancet. 2018 Oct 6;392(10154):1247-1256. doi: 10.1016/S0140-6736(18)31874-9.
5
Thrombotic thrombocytopenic purpura.血栓性血小板减少性紫癜。
Blood. 2017 May 25;129(21):2836-2846. doi: 10.1182/blood-2016-10-709857. Epub 2017 Apr 17.
6
Risk of venous thromboembolism occurrence among adults with selected autoimmune diseases: a study among a U.S. cohort of commercial insurance enrollees.特定自身免疫性疾病成年患者发生静脉血栓栓塞的风险：一项针对美国商业保险参保人群队列的研究
Thromb Res. 2015 Jan;135(1):50-7. doi: 10.1016/j.thromres.2014.10.012. Epub 2014 Oct 22.
7
Platelet-oriented inhibition in new TIA and minor ischemic stroke (POINT) trial: rationale and design.新型短暂性脑缺血发作和小面积缺血性卒中（POINT）试验中的血小板导向抑制：原理与设计。
Int J Stroke. 2013 Aug;8(6):479-83. doi: 10.1111/ijs.12129.
8
Ischemic stroke in the setting of chronic immune thrombocytopenia in an elderly patient--a therapeutic dilemma.老年患者慢性免疫性血小板减少症背景下的缺血性脑卒中——治疗困境。
Clin Appl Thromb Hemost. 2012 Jun;18(3):324-6. doi: 10.1177/1076029611425380. Epub 2011 Nov 14.
9
Cerebral infarction in idiopathic thrombocytopenic purpura: a case report.特发性血小板减少性紫癜合并脑梗死：一例报告
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.04.2009.1748. Epub 2009 Jun 4.
10
Recurrent ischemic stroke in a patient with idiopathic thrombocytopenic purpura.特发性血小板减少性紫癜患者的复发性缺血性卒中。
J Thromb Thrombolysis. 2010 Aug;30(2):229-32. doi: 10.1007/s11239-009-0431-2.