Chapiolkina Volha, Mekonen Yemesrach F, Guevara Nehemias, Perez Esmirna, Sanchez Jorge, Tole Maria C, Vigoda Ivette
Internal Medicine, St. Barnabas Hospital Health System, New York, USA.
Medicine, St. Barnabas Hospital Health System, New York, USA.
Cureus. 2024 Jul 24;16(7):e65283. doi: 10.7759/cureus.65283. eCollection 2024 Jul.
Thrombocytopenia is a condition in which the platelet count is less than 150,000/μL, which can be congenital or acquired. The condition can be further sub-classified. Nevertheless, the causes include infection, medication-mediated, liver diseases, or heart diseases. Moreover, diagnosis is straightforward only on a few occasions. Here, we are presenting a patient with a conundrum of immune thrombocytopenia (ITP) and a stroke. A 75-year-old female patient with a past medical history of hypertension was brought to the emergency department (ED) for altered mental status (AMS). Initial blood workup showed a platelet count of 27,000/μL and hemoglobin level of 6.2 g/dl, and brain magnetic resonance imaging (MRI) revealed ischemic stroke. Rarely, ITP patients can paradoxically develop arterial and venous thrombosis. Hence, physicians must remain vigilant in promptly and accurately diagnosing thrombotic events in ITP to ensure appropriate treatment, including antiplatelet and anticoagulant therapy, alongside ITP-specific interventions to improve outcomes.
血小板减少症是一种血小板计数低于150,000/μL的病症，可分为先天性或后天性。该病症还可进一步细分。然而，其病因包括感染、药物介导、肝脏疾病或心脏疾病。此外，仅在少数情况下诊断较为简单直接。在此，我们报告一名患有免疫性血小板减少症（ITP）且并发中风的患者。一名75岁女性患者，既往有高血压病史，因精神状态改变（AMS）被送至急诊科（ED）。初始血液检查显示血小板计数为27,000/μL，血红蛋白水平为6.2 g/dl，脑部磁共振成像（MRI）显示为缺血性中风。罕见的是，ITP患者可能反常地发生动脉和静脉血栓形成。因此，医生必须保持警惕，及时准确地诊断ITP中的血栓形成事件，以确保进行适当的治疗，包括抗血小板和抗凝治疗，以及ITP特异性干预措施以改善预后。
