Suppr超能文献

2型糖尿病、身体活动与神经肌肉骨骼并发症

Type 2 diabetes mellitus, physical activity, and neuromusculoskeletal complications.

作者信息

Jena Debasish, Sahoo Jagannatha, Barman Apurba, Behera Kishore Kumar, Bhattacharjee Souvik, Kumar Sanyal

机构信息

Department of Physical Medicine and Rehabilitation, All India Institute of Medical Sciences, Bhubaneswar Odisha, India.

Department of Endocrinology, All India Institute of Medical Sciences, Bhubaneswar Odisha, India.

出版信息

J Neurosci Rural Pract. 2022 Oct-Dec;13(4):705-710. doi: 10.25259/JNRP_11_2022. Epub 2022 Dec 2.

Abstract

OBJECTIVES

The objectives of the study were to investigate the neuromusculoskeletal complications of Type 2 diabetes mellitus (T2DM) and their associated factors, including the level of physical activity (PA) and clinicodemographic characteristics.

MATERIALS AND METHODS

In this cross-sectional analysis, we included 370 participants diagnosed with T2DM for no <1 year who satisfied the inclusion and exclusion criteria. Demographic and clinical characteristics were noted and a thorough clinical examination was performed on all the participants. International PA Questionnaire-Short Form was used to evaluate the level of PA of the participants. The continuous data is presented as mean ± SD and the categorical data is presented as the number of participants (n) and percentage (%). A logistic regression model was used to investigate the predictors for the prevalence of the complications.

RESULTS

The mean duration of T2DM was 7.32 ± 5.53 years and the mean hemoglobin A1C (HbA1c) level (%) was 8.16±1.67. A majority of the participants were having uncontrolled diabetes with an HbA1c level ≥7.5% ( = 190; 51.35%). The level of PA was low in a substantial proportion of the participants ( = 276; 74.59%). A total of 162 (43.78%) participants were diagnosed with neuromusculoskeletal complications. Low back pain was the most common complication and degenerative disk disease was the most common diagnosis overall. Longer duration of diabetes, poor glycemic control, and low PA were associated with the prevalence of neuromusculoskeletal complications ( < 0.05).

CONCLUSION

Neuromusculoskeletal complications of T2DM are common and can result in significant disability in this population. Low PA is very common among T2DM patients and an important contributor to the development of complications. Health-care providers should consider PA an integral component of the management protocol for T2DM patients.

摘要

目的

本研究的目的是调查2型糖尿病(T2DM)的神经肌肉骨骼并发症及其相关因素,包括身体活动(PA)水平和临床人口统计学特征。

材料与方法

在这项横断面分析中,我们纳入了370名确诊T2DM不少于1年且符合纳入和排除标准的参与者。记录了人口统计学和临床特征,并对所有参与者进行了全面的临床检查。使用国际身体活动问卷简表评估参与者的PA水平。连续数据以均值±标准差表示,分类数据以参与者数量(n)和百分比(%)表示。使用逻辑回归模型研究并发症患病率的预测因素。

结果

T2DM的平均病程为7.32±5.53年,平均糖化血红蛋白(HbA1c)水平(%)为8.16±1.67。大多数参与者的糖尿病未得到控制,HbA1c水平≥7.5%(n = 190;51.35%)。相当一部分参与者的PA水平较低(n = 276;74.59%)。共有162名(43.78%)参与者被诊断患有神经肌肉骨骼并发症。腰痛是最常见的并发症,椎间盘退变疾病是总体上最常见的诊断。糖尿病病程较长、血糖控制不佳和PA水平较低与神经肌肉骨骼并发症的患病率相关(P < 0.05)。

结论

T2DM的神经肌肉骨骼并发症很常见,可导致该人群出现严重残疾。PA水平低在T2DM患者中非常普遍,是并发症发生的重要促成因素。医疗保健提供者应将PA视为T2DM患者管理方案的一个组成部分。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4c04/9893944/333c5a3c72dc/JNRP-13-705-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验