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新冠疫情对希腊癫痫患者队列的影响。

The impact of the Covid-19 pandemic on a Greek cohort of patients with epilepsy.

作者信息

Giza E, Lefkopoulou M, Dimitrakopoulos D, Karachristianou S, Liasidis C

机构信息

Department of Neurology, Hippokratio General Hospital of Thessaloniki, Thessaloniki, Greece.

Department of Biochemistry & Biotechnology, University of Thessaly and National Hellenic Research Foundation, Larissa, Greece.

出版信息

Hippokratia. 2021 Oct-Dec;25(4):145-150.

PMID:36743863
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9894308/
Abstract

BACKGROUND

The Covid-19 pandemic, the subsequent lockdown, and the measures of social distancing may have had adverse effects on patients with epilepsy (PWE). This study was designed to assess the pandemic's psychological impact on the Greek non-infected PWE and possible changes in their seizure control.

METHOD

The patients were evaluated utilizing a semi-structured interview consisting of open questions regarding their demographic, social, and clinical characteristics, followed by five questions (on a scale of 0-10) related to the Covid-19 pandemic, lockdown, and social distancing measures. Anxiety and depression of PWE were screened using the Hospital Anxiety and Depression Scale (HADS), which consists of HADS-Anxiety and HADS-Depression subscales.

RESULTS

We evaluated 65 PWE in the outpatient clinic (60 %) or via telephone interview (40 %). None of these patients experienced changes in seizure control. The mean scores of the Covid-19-related questions were 6.1 ± 2.7 (fear of getting infected), 4.7 ± 3.3 (fear of death), 7.1 ± 2.7 (fear of sickness for their relatives), 6.4 ± 3.1 (stress during lockdown), and 3.0 ± 2.9 (fear of antiepileptic drugs unavailability). Thirty-nine (60 %) patients screened positive for anxiety and thirty-three (50.8 %) for depression.

CONCLUSION

The psychological impact of the Covid-19 pandemic, lockdown, and social distancing measures on non-infected PWE was moderate without changes in their seizure control. HIPPOKRATIA 2021, 25 (4):145-150.

摘要

背景

新冠疫情、随后的封锁措施以及社交距离措施可能对癫痫患者产生了不利影响。本研究旨在评估疫情对希腊未感染癫痫患者的心理影响以及他们癫痫控制情况的可能变化。

方法

通过半结构化访谈对患者进行评估,访谈包括关于其人口统计学、社会和临床特征的开放性问题,随后是五个与新冠疫情、封锁和社交距离措施相关的问题(0-10分制)。使用医院焦虑抑郁量表(HADS)对癫痫患者的焦虑和抑郁进行筛查,该量表由HADS焦虑分量表和HADS抑郁分量表组成。

结果

我们在门诊对65名癫痫患者进行了评估(60%),或通过电话访谈进行评估(40%)。这些患者中没有一人的癫痫控制情况发生变化。与新冠相关问题的平均得分分别为:6.1±2.7(担心被感染)、4.7±3.3(担心死亡)、7.1±2.7(担心亲属患病)、6.4±3.1(封锁期间的压力)和3.0±2.9(担心抗癫痫药物无法获得)。39名(60%)患者焦虑筛查呈阳性,33名(50.8%)患者抑郁筛查呈阳性。

结论

新冠疫情、封锁和社交距离措施对未感染癫痫患者的心理影响为中度,且他们的癫痫控制情况未发生变化。《希波克拉底》2021年,第25卷(4):145-150。

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Seizure. 2021 May;88:102-108. doi: 10.1016/j.seizure.2021.03.029. Epub 2021 Mar 31.
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J Clin Neurol. 2021 Apr;17(2):176-186. doi: 10.3988/jcn.2021.17.2.176.
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