Lodhia Jay, Urassa Ellyagape, Mremi Alex
Department of General Surgery, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.
Faculty of Medicine, Kilimanjaro Christian Medical University College, Moshi, Tanzania.
SAGE Open Med Case Rep. 2023 Jan 25;11:2050313X231151753. doi: 10.1177/2050313X231151753. eCollection 2023.
Paget's disease of the breast is a rare pathology resulting from abnormal proliferation of glandular epithelial cells in the nipple-areolar epidermis. The disease is named after James Paget, a pathologist and surgeon, who reported a relationship between a nipple rash and mammary gland tumors in 1874. Early diagnosis may be quite difficult. Histopathology can give the definitive diagnosis and the treatment depends upon the presence or absence of an associated breast lump. The treatment options include simple lumpectomy, mastectomy or radical mastectomy depending upon the lump (cancer) in the diseased breast. Herein, we present a case of Paget's disease of the breast presented with a long history of nipple eczema.
乳腺佩吉特病是一种罕见的病理状况，由乳头乳晕表皮的腺上皮细胞异常增殖引起。该疾病以病理学家兼外科医生詹姆斯·佩吉特的名字命名，他在1874年报告了乳头皮疹与乳腺肿瘤之间的关联。早期诊断可能相当困难。组织病理学可给出明确诊断，治疗则取决于是否存在相关的乳腺肿块。治疗选择包括单纯乳房肿块切除术、乳房切除术或根治性乳房切除术，具体取决于患侧乳房的肿块（癌症）情况。在此，我们呈现一例伴有长期乳头湿疹病史的乳腺佩吉特病病例。
