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一名再生障碍性贫血患儿出现不同层面的严重视网膜出血伴浆液性视网膜脱离——病例报告

Severe retinal hemorrhages at various levels with a serous retinal detachment in a pediatric patient with aplastic anemia-A case report.

作者信息

Jiang Xiaoshuang, Shen Mengxi, Liang Licong, Rosenfeld Philip J, Lu Fang

机构信息

Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, China.

Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, United States.

出版信息

Front Med (Lausanne). 2023 Jan 18;10:1051089. doi: 10.3389/fmed.2023.1051089. eCollection 2023.

DOI:10.3389/fmed.2023.1051089
PMID:36744127
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9889655/
Abstract

BACKGROUND

Aplastic anemia can cause ophthalmic abnormalities in patients. Vision loss in a child with aplastic anemia due to massive retinal hemorrhages at various levels is rare.

CASE PRESENTATION

A pediatric patient with aplastic anemia presented with retinal hemorrhages at multiple levels along with a serous retinal detachment in both eyes and subsequent retinal changes after pars plana vitrectomy.

CONCLUSION

Anemia and thrombocytopenia in aplastic anemia could cause severe retinal hemorrhages and result in retinal atrophy and retinal edema. Vitrectomy can be performed to remove vitreous hemorrhage, but risk factors for retinal atrophy and edema need further investigation.

摘要

背景

再生障碍性贫血可导致患者出现眼部异常。因不同层面大量视网膜出血导致再生障碍性贫血患儿视力丧失的情况较为罕见。

病例介绍

一名再生障碍性贫血患儿出现双眼多层面视网膜出血、浆液性视网膜脱离，以及玻璃体切除术后的视网膜变化。

结论

再生障碍性贫血中的贫血和血小板减少可导致严重的视网膜出血，并导致视网膜萎缩和视网膜水肿。可进行玻璃体切除术以清除玻璃体积血，但视网膜萎缩和水肿的危险因素需要进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e4e/9889655/8c30e07e78cd/fmed-10-1051089-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e4e/9889655/87194f749326/fmed-10-1051089-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e4e/9889655/d59ccd03088c/fmed-10-1051089-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e4e/9889655/8c30e07e78cd/fmed-10-1051089-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e4e/9889655/87194f749326/fmed-10-1051089-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e4e/9889655/d59ccd03088c/fmed-10-1051089-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e4e/9889655/8c30e07e78cd/fmed-10-1051089-g003.jpg

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Aplastic anaemia: Current concepts in diagnosis and management.再生障碍性贫血：诊断与管理的当前概念
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