Department of Anesthesiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
Department of Neuropsychology, Kennedy Krieger Institute.
J Neurosurg Anesthesiol. 2023 Jan 1;35(1):124-126. doi: 10.1097/ANA.0000000000000878. Epub 2022 Dec 6.
Neurodevelopmental outcomes research in children following extracorporeal membrane oxygenationis a complex and evolving field. From systematic reviews to multi-center prospective cohort studies, a variety of research endeavors in this domain have already been conducted. Recent attention has redirected the focus on biomarkers and imaging studies to help better understand the neurological, developmental, and behavioral effects of extracorporeal membrane oxygenation on surviving children. This review provides an overview of major research in the field, ongoing and future studies, and a summary of lessons learned from these efforts.
体外膜肺氧合(ECMO)后儿童的神经发育结局研究是一个复杂且不断发展的领域。从系统评价到多中心前瞻性队列研究,该领域已经开展了各种研究工作。最近,人们的注意力重新集中在生物标志物和影像学研究上,以帮助更好地了解 ECMO 对幸存儿童的神经、发育和行为影响。本文综述了该领域的主要研究、正在进行和未来的研究,并总结了这些研究的经验教训。