Kaiser Permanente Bernard J Tyson School of Medicine, Pasadena, CA.
Kaiser Los Angeles Medical Center, Department of Orthopedics, Los Angeles, CA.
Spine (Phila Pa 1976). 2023 Jun 15;48(12):E188-E195. doi: 10.1097/BRS.0000000000004592. Epub 2023 Feb 6.
Retrospective matched cohort study.
The aim of this study was to determine whether females with idiopathic scoliosis (IS), both with and without spine fusion, experience different rates of cesarean section (CS) and epidural anesthesia (EA) than females without scoliosis.
IS is a common spine condition with a higher prevalence in females. It is unclear whether females with scoliosis, treated nonoperatively or operatively, have different rates of cesarean delivery or EA.
Patients with IS who delivered in our integrated health care system during a 6-year period were identified (N = 1810). They were matched with a group without scoliosis who delivered during the same period (N = 1810). Rates and relative risk (RR) of CS and EA between cohorts and subgroups were calculated.
The scoliosis cohort had significantly higher rates and RR of EA ( P = 0.002 and P = 0.004, respectively). Scoliosis patients treated nonoperatively had an 8% greater RR of EA ( P = 0.004) and had a significantly lower rate of CS (23.2% vs . 26%, P = 0.048) compared with the control group. Among only scoliosis patients, those treated with spine fusion had a 38% decreased RR of EA ( P < 0.001). Distal fusion level did not seem to influence the RR of EA or CS.
Females with scoliosis were significantly more likely to receive EA at delivery compared with females without scoliosis. Rates and RR of cesarean delivery were not significantly lower among women with scoliosis, but females treated nonoperatively for scoliosis had a significantly lower CS rate than those without scoliosis. Females treated with spine fusion for scoliosis were far less likely to receive EA than both females without scoliosis and females with scoliosis treated nonoperatively.
回顾性匹配队列研究。
本研究旨在确定特发性脊柱侧凸(IS)女性(无论是否接受脊柱融合术)接受剖宫产(CS)和硬膜外麻醉(EA)的比率是否与无脊柱侧凸的女性不同。
IS 是一种常见的脊柱疾病,女性患病率较高。目前尚不清楚接受非手术或手术治疗的脊柱侧凸女性的剖宫产率或 EA 率是否存在差异。
在我们的综合医疗保健系统中,确定了在 6 年期间分娩的 IS 患者(N=1810)。他们与同期分娩的无脊柱侧凸组(N=1810)相匹配。计算两组队列和亚组的 CS 和 EA 发生率和相对风险(RR)。
脊柱侧凸组 EA 发生率和 RR 显著更高(P=0.002 和 P=0.004)。与对照组相比,接受非手术治疗的脊柱侧凸患者 EA 的 RR 增加 8%(P=0.004),CS 发生率显著降低(23.2%比 26%,P=0.048)。在仅脊柱侧凸患者中,接受脊柱融合术治疗的患者 EA 的 RR 降低了 38%(P<0.001)。融合的远端水平似乎不影响 EA 或 CS 的 RR。
与无脊柱侧凸的女性相比,患有脊柱侧凸的女性在分娩时接受 EA 的可能性明显更高。脊柱侧凸女性的剖宫产率并没有显著降低,但接受非手术治疗的脊柱侧凸女性的 CS 率明显低于无脊柱侧凸的女性。接受脊柱融合术治疗的脊柱侧凸女性接受 EA 的可能性远低于无脊柱侧凸的女性和接受非手术治疗的脊柱侧凸女性。