From the Shengli Clinical Medical College of Fujian Medical University, Fujian Medical University, Fuzhou, China (Liu, Huang, Wu); State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong, China (Yu); Department of Ophthalmology, Fujian Provincial Hospital, Fuzhou, China (Li, Wu).
J Cataract Refract Surg. 2023 May 1;49(5):492-498. doi: 10.1097/j.jcrs.0000000000001152. Epub 2023 Feb 1.
To evaluate intraocular lens (IOL) tilt and decentration and their effects on higher-order aberrations (HOAs) after cataract surgery with and without primary posterior continuous curvilinear capsulorhexis (PPCCC).
Fujian Provincial Hospital, Fujian, China.
Prospective, intraindividual, randomized, comparative clinical trial.
64 eyes of 32 patients with age-related cataract who underwent bilateral cataract surgery and IOL implantation were enrolled in this study. In randomized order, all patients had phacoemulsification cataract surgery with PPCCC in 1 eye (PPCCC group) and routine cataract surgery in the contralateral eye (NPCCC group). IOL decentration, tilt, HOAs, modulation transfer function, and point spread function were measured at 1 day, 1 week, 1 month, and 3 months after surgery using OPD-Scan III.
52 eyes of 26 patients were available for analysis. The mean overall decentration in the NPCCC group was significantly higher than in the PPCCC group at 3 months (0.302 ± 0.157 mm vs 0.187 ± 0.099 mm, P < .001). Under 3 mm pupil, internal spherical aberration (SA) 1 day after surgery and coma 1 week after surgery were lower in the PPCCC group compared with the NPCCC group (0.15 ± 0.10 μm vs 0.30 ± 0.21 μm, P < .001, and 0.34 ± 0.18 μm vs 0.47 ± 0.31 μm, P = .03, respectively). IOL decentration was significantly correlated with ocular and internal coma, ocular and internal SA, and internal HOAs at 5 mm pupil ( R = 0.083 and R = 0.099, R = 0.650 and R = 0.613, and R = 0.418, respectively, all P < .01).
Less IOL decentration was observed in the PPCCC group at 3 months after surgery, indicating that PPCCC may result in better IOL centrality.
评估白内障术后人工晶状体（IOL）倾斜和偏心及其对伴有和不伴有原发性后连续曲线囊膜环形撕除术（PPCCC）的高阶像差（HOAs）的影响。
中国福建省立医院。
前瞻性、个体内、随机、对照临床试验。
本研究纳入 32 例年龄相关性白内障患者的 64 只眼，均行双眼白内障超声乳化吸除术联合 IOL 植入术。所有患者按随机顺序分为两组，一组行超声乳化白内障吸除术联合 PPCCC（PPCCC 组），另一组行常规白内障超声乳化吸除术（NPCCC 组）。术后 1 天、1 周、1 个月和 3 个月，使用 OPD-Scan III 测量 IOL 偏心、倾斜、HOAs、调制传递函数和点扩散函数。
26 例患者的 52 只眼纳入分析。NPCCC 组术后 3 个月总偏心度明显高于 PPCCC 组（0.302±0.157mm 比 0.187±0.099mm，P<.001）。在 3mm 瞳孔下，PPCCC 组术后 1 天的球差和 1 周的彗差均低于 NPCCC 组（0.15±0.10μm 比 0.30±0.21μm，P<.001，和 0.34±0.18μm 比 0.47±0.31μm，P=.03）。在 5mm 瞳孔下，IOL 偏心与眼内彗差、眼内球差和眼内 HOAs 显著相关（R=0.083 和 R=0.099，R=0.650 和 R=0.613，R=0.418，均 P<.01）。
术后 3 个月时，PPCCC 组的 IOL 偏心度较小，表明 PPCCC 可能导致更好的 IOL 中心定位。
