Shengli Clinical Medical College of Fujian Medical University; Fujian Medical University, Fuzhou, China.
Department of Ophthalmology, Fujian Provincial Hospital, Fuzhou, China.
PLoS One. 2024 Mar 22;19(3):e0299064. doi: 10.1371/journal.pone.0299064. eCollection 2024.
This study aimed to assess the repeatability of intraocular lens (IOL) decentration measurements obtained through Pentacam, based on corneal topographic axis (CTA) and pupillary axis (PA), and to evaluate the level of agreement between Pentacam and OPD-Scan III devices in measuring IOL decentration.
In this prospective observational case series, three measurements were performed with Pentacam to evaluate the repeatability of the measurements. The analysis included the calculation of the mean and standard deviations (SD), conducting a repeated measures analysis of variance (rANOVA), and determining an intraclass correlation coefficient (ICC) to assess the repeatability of the measurements. Moreover, Bland-Altman analysis was employed to assess the agreement between Pentacam and OPD-Scan III devices in measuring IOL decentration. IOL decentration measurements were obtained with respect to both CTA and PA.
A total of 40 eyes from 40 patients were analyzed. The rANOVA revealed no significant difference among three consecutive measurements of IOL decentration obtained with Pentacam. The mean SD of all parameters ranged from 0.04 mm to 0.07 mm. With CTA as the reference axis, the ICC values for Pentacam measurements of IOL decentration were 0.82 mm for the X-axis, 0.76 mm for the Y-axis, and 0.82 mm for spatial distance. When using PA as the reference axis, the corresponding ICC values were 0.87, 0.89, and 0.77, respectively. The 95% limits of agreement for all IOL decentration measurements were wide when comparing Pentacam and OPD-Scan III.
Pentacam demonstrated high repeatability in measuring IOL decentration with respect to both CTA and PA. However, due to poor agreement between Pentacam and OPD-Scan III measurements, caution should be exercised when using data interchangeably between the two devices.
本研究旨在评估基于角膜地形轴（CTA）和瞳孔轴（PA）的 Pentacam 测量人工晶状体（IOL）偏心度的重复性，并评估 Pentacam 与 OPD-Scan III 设备在测量 IOL 偏心度方面的一致性。
本前瞻性观察性病例系列研究中，使用 Pentacam 进行了三次测量，以评估测量的重复性。分析包括计算平均值和标准差（SD）、进行重复测量方差分析（rANOVA）以及确定组内相关系数（ICC）以评估测量的重复性。此外，采用 Bland-Altman 分析评估 Pentacam 与 OPD-Scan III 设备在测量 IOL 偏心度方面的一致性。以 CTA 和 PA 为参考轴，分别对 IOL 偏心度进行测量。
共分析了 40 例患者的 40 只眼。rANOVA 显示 Pentacam 三次连续测量的 IOL 偏心度无显著差异。所有参数的平均 SD 范围为 0.04 至 0.07mm。以 CTA 为参考轴，Pentacam 测量的 IOL 偏心度 X 轴、Y 轴和空间距离的 ICC 值分别为 0.82、0.76 和 0.82。以 PA 为参考轴时，相应的 ICC 值分别为 0.87、0.89 和 0.77。与 OPD-Scan III 相比，所有 IOL 偏心度测量的 95%一致性界限均较宽。
Pentacam 测量 CTA 和 PA 参考轴的 IOL 偏心度具有较高的重复性。然而，由于 Pentacam 与 OPD-Scan III 之间的测量一致性较差，因此在这两种设备之间交换数据时应谨慎使用。
