Coleman R J, Blackwood J M, Swan K G
Department of Surgery, UMDNJ-New Jersey Medical School, Newark.
Am Surg. 1987 Oct;53(10):584-6.
This report examines the efficacy of preoperative antibiotics in cases of nonperforated appendicitis. The charts of 61 patients who had an operative and pathologic diagnosis of acute nonperforated appendicitis were reviewed. Thirty-one patients received preoperative cephalosporins, and in one patient (3.2%) a subsequent wound infection developed. Of 30 patients who did not receive preoperative antibiotics, four (13.2%) patients developed septic complications. The difference in postoperative septic complications between these groups is not statistically significant (P = .3310). Preoperative prophylaxis with cephalosporins in cases of nonperforated appendicitis is not indicated.
本报告探讨了术前使用抗生素在非穿孔性阑尾炎病例中的疗效。回顾了61例经手术及病理诊断为急性非穿孔性阑尾炎患者的病历。31例患者术前接受了头孢菌素治疗，其中1例（3.2%）随后发生了伤口感染。在30例未接受术前抗生素治疗的患者中，有4例（13.2%）发生了感染性并发症。这些组之间术后感染性并发症的差异无统计学意义（P = 0.3310）。非穿孔性阑尾炎病例中不建议术前使用头孢菌素进行预防。
