评估一种新型的、便携式的、可自我管理的设备（“Beacon”），该设备通过测量临界闪烁频率来测试肝性脑病。
Evaluating a Novel, Portable, Self-Administrable Device ("Beacon") That Measures Critical Flicker Frequency as a Test for Hepatic Encephalopathy.
机构信息
University of Washington, Division of Gastroenterology and Hepatology, Seattle, Washington, USA.
Department of Medicine Veterans Affairs Puget Sound Healthcare System and University of Washington, Seattle, Washington, USA.
出版信息
Am J Gastroenterol. 2023 Jun 1;118(6):1096-1100. doi: 10.14309/ajg.0000000000002211. Epub 2023 Feb 3.
INTRODUCTION
We compared critical flicker frequency (CFF) thresholds obtained using a novel portable device "Beacon" with thresholds from the commercially available Lafayette Flicker Fusion System (Lafayette-FFS) in patients with cirrhosis.
METHODS
One hundred fifty-three participants with chronic liver disease underwent CFF testing using Beacon and Lafayette-FFS with a method-of-limits and/or forced-choice protocol.
RESULTS
Beacon demonstrated excellent test-retest reliability (intraclass correlation 0.91-0.97) and good correlation with the Lafayette-FFS values (intraclass correlation 0.77-0.84). Forced-choice CFF were on average 4.1 Hz higher than method-of-limits descending CFFs.
DISCUSSION
Beacon can be self-administered by patients with chronic liver disease and cirrhosis to measure CFF, a validated screening test for minimal hepatic encephalopathy.
简介
我们比较了使用新型便携式设备“Beacon”获得的临界闪烁频率（CFF）阈值与 Lafayette 闪烁融合系统（Lafayette-FFS）的商业可用阈值，该系统用于肝硬化患者。
方法
153 名慢性肝病患者使用 Beacon 和 Lafayette-FFS 进行 CFF 测试，采用极限法和/或迫选法方案。
结果
Beacon 表现出极好的测试-重测可靠性（组内相关系数 0.91-0.97），与 Lafayette-FFS 值具有良好的相关性（组内相关系数 0.77-0.84）。迫选 CFF 平均比极限法下降 CFF 高 4.1Hz。
讨论
Beacon 可由慢性肝病和肝硬化患者自行使用，以测量临界闪烁频率（CFF），这是一种用于最小型肝性脑病的验证性筛选测试。
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