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[浅表性剥脱性食管炎:多病患者中诊断不足的疾病实体]

[Esophagitis dissecans superficialis: subdiagnosed entity in multi-morbid patients].

作者信息

Berrospi Castillo Diego, Kapsoli María Del Carmen, Benites Goñi Harold E

机构信息

Hospital Nacional Edgardo Rebagliati Martins. Lima, Perú.

Universidad San Ignacio de Loyola. Lima, Perú.

出版信息

Rev Gastroenterol Peru. 2022 Jul-Sep;42(3):199-202.

PMID:36746502
Abstract

A 76-year-old patient presents multiple comorbidities and gastrointestinal symptoms. The upper gastrointestinal endoscopy exam reveals distal stiffness esophageal mucosa. A biopsy was taking creating sloughing of 20 mm long by 6 mm wide with self-limited bleeding. Specimen is compatible with Esophagitis Dissecans Superficialis (EDS). This is a rare entity first described in 1800, characterized endoscopically by mucosal detachment in vertical strips like "gift paper tape", which is confirmed by pathology with a mucosa with "two tones", composed of a eosinophilic superficial layer and a normal-appearing basophilic area. It may be accompanied by minimal focal inflammation. The etiopathogenesis is not clear; however, it has a good response to proton pump inhibitors (PPIs). In our case, the patient presented all the characteristics of EDS, and given its low reported frequency, a review of the literature and discussion of this rare entity was performed.

摘要

一名76岁患者存在多种合并症及胃肠道症状。上消化道内镜检查显示食管远端黏膜僵硬。进行了活检,造成了一处长20毫米、宽6毫米的组织脱落,并伴有自限性出血。标本符合浅表性剥脱性食管炎(EDS)。这是一种罕见病症,于1800年首次被描述,内镜特征为黏膜呈垂直条带状脱落,类似“礼品纸带”,病理检查证实黏膜有“两种色调”,由嗜酸性表层和外观正常的嗜碱性区域组成。它可能伴有轻微的局灶性炎症。病因发病机制尚不清楚;然而,它对质子泵抑制剂(PPI)反应良好。在我们的病例中,患者呈现出EDS的所有特征,鉴于其报道频率较低,我们对该罕见病症进行了文献回顾及讨论。

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