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[浅表性剥脱性食管炎:两例相同罕见病例]

[Esophagitis dissecans superficialis: two cases of the same rare entity].

作者信息

Ollero Domenche Leticia, Del Valle Sánchez María Elena, Abecia Martínez Emilio Ignacio, Hörndler Argárate Carlos

机构信息

Servicio de Anatomía Patológica, Hospital Universitario Miguel Servet, Zaragoza, España.

Servicio de Anatomía Patológica, Hospital Universitario Miguel Servet, Zaragoza, España.

出版信息

Rev Esp Patol. 2024 Apr-Jun;57(2):133-136. doi: 10.1016/j.patol.2023.11.002. Epub 2023 Dec 26.

Abstract

Esophagitis dissecans superficialis (EDS) is a rare disease characterized by sloughing of the superficial esophageal mucosa and, histologically, by the bitonal appearance of the squamous epithelium secondary to necrosis of the most superficial layers. Etiology is uncertain, however, it has been associated with some medications, autoimmune diseases, esophageal stasis and endoscopic procedures. Here, two cases are presented, one of them which appeared in a woman after an episode of dysphagia and another one which occurred to a man with comorbidities and epigastric pain. This entity should be considered due to its self-limiting clinical course, compared to other entities with a more torpid evolution or that require more specific treatment.

摘要

浅表性剥脱性食管炎(EDS)是一种罕见疾病,其特征为食管浅表黏膜脱落,组织学表现为最表层坏死继发鳞状上皮的双向外观。病因尚不确定,然而,它与某些药物、自身免疫性疾病、食管淤滞和内镜操作有关。本文报告两例病例,其中一例发生在一名女性吞咽困难发作之后,另一例发生在一名患有多种合并症且有上腹部疼痛的男性身上。鉴于其临床病程为自限性,与其他进展较缓慢或需要更特殊治疗的疾病相比,应考虑到这种疾病。

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