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葡萄牙经导管主动脉瓣植入术的空间分析及相关因素:2015 年至 2017 年的回顾性分析。

Spatial analysis and factors associated with transcatheter aortic valve implantation in Portugal: a retrospective analysis from 2015 to 2017.

机构信息

NOVA National School of Public Health, NOVA University Lisbon, Lisbon, Portugal

NOVA National School of Public Health, Public Health Research Center, CISP, NOVA University Lisbon, Lisbon, Portugal.

出版信息

BMJ Open. 2023 Feb 6;13(2):e070715. doi: 10.1136/bmjopen-2022-070715.

Abstract

OBJECTIVES

To identify the factors associated with transcatheter aortic valve implantation (TAVI) use of TAVI in inpatients with aortic stenosis (AS) in Portugal and its geographical distribution.

METHODS

A quantitative, observational and retrospective study using the Portuguese National Health Service inpatient discharge database from 2015 to 2017. Surgical aortic valve replacement (SAVR) and TAVI procedures were selected using the International Classification of Diseases. First, we mapped the yearly age-standardised rate for each procedure using QGIS. Then, we performed χ tests, independent t-tests and logistic regressions to study the factors associated with TAVI use.

RESULTS

From 2015 to 2017, 8398 hospitalisations were selected, 88.5% SAVR and 11.5% TAVI. From 2015 to 2017, SAVR use increased in the Northern region and decreased in the Lisbon region, while the opposite was observed for TAVI. TAVI was performed among the most complex (p<0.001) and older patients (the mean (SD) age for SAVR was 70 (±11) years old and 81 (±7) years old for TAVI, p<0.001). The results for the logistic regressions showed that, more recent hospitalisations, being older, living in the Lisbon region and having a higher Charlson Comorbidity Index was associated with an increased likelihood of undergoing TAVI (p<0.001).

CONCLUSIONS

TAVI increased over the years. TAVI is more often performed in more severe patients as an alternative to SAVR with similar discharge outcomes. These results suggest the existence of geographic disparities in the availability and access to healthcare services and technologies.

摘要

目的

确定与葡萄牙主动脉瓣狭窄(AS)住院患者经导管主动脉瓣植入术(TAVI)使用相关的因素及其地域分布。

方法

采用葡萄牙国家卫生服务住院患者出院数据库,对 2015 年至 2017 年进行了一项定量、观察性和回顾性研究。使用国际疾病分类选择了主动脉瓣置换术(SAVR)和 TAVI 手术。首先,我们使用 QGIS 绘制了每种手术每年的年龄标准化率图。然后,我们进行了卡方检验、独立 t 检验和逻辑回归分析,以研究与 TAVI 使用相关的因素。

结果

2015 年至 2017 年期间,共选择了 8398 例住院患者,其中 88.5%为 SAVR,11.5%为 TAVI。2015 年至 2017 年期间,SAVR 的使用在北部地区增加,而在里斯本地区减少,而 TAVI 的使用则相反。TAVI 主要用于最复杂的患者(p<0.001)和年龄较大的患者(SAVR 的平均(SD)年龄为 70(±11)岁,TAVI 为 81(±7)岁,p<0.001)。逻辑回归的结果表明,最近的住院治疗、年龄较大、居住在里斯本地区和Charlson 合并症指数较高与 TAVI 可能性增加相关(p<0.001)。

结论

TAVI 手术的数量逐年增加。TAVI 更多地用于病情更严重的患者,作为 SAVR 的替代方案,其出院结果相似。这些结果表明,在医疗保健服务和技术的可用性和可及性方面存在地域差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/174b/9906166/b736a55efa12/bmjopen-2022-070715f01.jpg

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