Verkkala K, Harjula A, Valtonen V, Järvinen A, Maamies T
Department of Thoracic and Cardiovascular Surgery, University Central Hospital, Helsinki, Finland.
Ann Chir Gynaecol. 1987;76(3):139-44.
Nine cases of proven early form of endocarditis occurred after open-heart surgery. Eight of these occurred after valve surgery with an incidence 0.7% while one complicated correction of Fallot's tetralogy. Sternal wound infection preceeded endocarditis in two cases and respiratory tract infection in one case. In these three patients, the infection was caused by the same bacteria as the subsequent postoperative endocarditis. In only one patient were there no signs of infection during the immediate postoperative course. A new cardiac murmur suggesting prosthetic malfunction was a clear indication for early reoperation in five patients; four of them survived. In one patient with a paravalvular leakage the decision to operate was delayed with fatal outcome. Generally, in patients without signs of prosthetic valve malfunction or other prosthetic complication the indication and timing of surgery is problematic. In our series the antibiotic therapy was continued over two months in three patients. Two of them died while the third patient was operated on successfully.
9例经证实的早期心内膜炎发生于心脏直视手术后。其中8例发生在瓣膜置换术后,发生率为0.7%,1例发生在法洛四联症矫正术后。2例心内膜炎患者术前有胸骨伤口感染,1例有呼吸道感染。这3例患者的感染病原菌与随后发生的术后心内膜炎相同。仅1例患者术后早期无感染迹象。5例患者出现提示人工瓣膜功能障碍的新心脏杂音,这是早期再次手术的明确指征;其中4例存活。1例人工瓣膜周漏患者延迟手术,最终死亡。一般来说,对于无人工瓣膜功能障碍或其他人工瓣膜并发症迹象的患者,手术指征和时机存在问题。在我们的系列病例中,3例患者抗生素治疗持续了两个多月。其中2例死亡,第3例手术成功。