Peace Odiase, Terry Henry, Banga Amita, Rachakonda Kartik, Garg Amar P, Rachakonda Girish
Meharry Medical College.
Shobhit University.
Res Sq. 2023 Jan 27:rs.3.rs-2043805. doi: 10.21203/rs.3.rs-2043805/v1.
COVID-19 is a viral infection that resulted in a global pandemic. In the United States, COVID-19 caused incommensurate deaths, especially among members of minority groups. Previous literature shows comorbidities such as hypertension (HTN), diabetes mellitus (DM) and obesity (OBS) have been implicated in the severity of COVID-19 cases regardless of racial or ethnic group classification. However, minority populations, particularly people of African descent experienced higher mortality as they carry a disproportionately heavier burden in comorbidities cases. In this study we first confirm current literature on COVID-19 incidence and its correlation with the prevalence of comorbidities in various racial and ethnic populations, using anonymous and aggregated data from the Nashville General Hospital at Meharry, an Institute for the Study of Minority Health. We also evaluated the prevalence of comorbidities in minority patients and computed the correlation between the COVID-19 incidence and a permuted prevalence of comorbidities. A total of 959 patients were reviewed and our study indicates COVID-19 patients classified as Non-Hispanic Blacks (NHB) were approximately 3 times more likely to have an HTN or DM or both HTN and DM diagnosis. The chances double to be approximately six times higher when an OBS diagnosis is included singularly or in conjunction with either HTN or DM or both HTN and DM.
新冠病毒病(COVID-19)是一种导致全球大流行的病毒感染。在美国,COVID-19造成了不相称的死亡,尤其是在少数群体成员中。先前的文献表明,无论种族或族裔群体分类如何,高血压(HTN)、糖尿病(DM)和肥胖症(OBS)等合并症都与COVID-19病例的严重程度有关。然而,少数族裔人口,特别是非洲裔美国人,由于他们在合并症病例中承担着不成比例的更重负担,死亡率更高。在本研究中,我们首先使用梅哈里纳什维尔综合医院(一家少数族裔健康研究机构)的匿名汇总数据,证实了当前关于COVID-19发病率及其与不同种族和族裔人群中合并症患病率相关性的文献。我们还评估了少数族裔患者中合并症的患病率,并计算了COVID-19发病率与合并症置换患病率之间的相关性。总共对959名患者进行了审查,我们的研究表明,被归类为非西班牙裔黑人(NHB)的COVID-19患者被诊断患有HTN或DM或同时患有HTN和DM的可能性大约高出3倍。当单独或与HTN或DM或同时患有HTN和DM一起包括OBS诊断时,可能性会翻倍,大约高出6倍。