经导管主动脉瓣植入术的经济学：一项系统评价。
The economics of TAVI: A systematic review.
作者信息
Petrou Panagiotis
机构信息
University of Nicosia, School of Sciences and Engineering, Pharmacy School, Pharmacoepidemiology-Pharmacovigilance, Nicosia, Cyprus.
University of Nicosia, Department of Life and Health Sciences, School of Sciences and Engineering, Pharmacoepidemiology-Pharmacovigilance, Nicosia, Cyprus.
出版信息
Int J Cardiol Heart Vasc. 2023 Jan 25;44:101173. doi: 10.1016/j.ijcha.2023.101173. eCollection 2023 Feb.
OBJECTIVE
The scope of this systematic review is to update the existing body of evidence regarding the cost-effectiveness of transcatheter aortic valve implantation, stratified across all risk categories, and to assess their methodological quality.
METHODS
A systematic review was performed including published cost-effectiveness analyses of heart valve implantations. The quality was assessed with the Quality of Health Economics Tool.
RESULTS
We identified 33 economic evaluations of transcatheter aortic heart valve implantations. Results were not consistent, ranging from dominant to dominating. Moreover, the models were sensitive to an array of variables. The methodological quality of the studies was good.
CONCLUSION
This systematic review led to inconclusive and inconsistent results pertinent to the economic profile of TAVI technology. It also highlighted areas which merit further research regarding the pillars of cost-effectiveness analysis such as modeling, the extrapolation of available data and the uncertainty of the evidence. A thorough assessment of the patient should proceed any decision-making.
目的
本系统评价的范围是更新关于经导管主动脉瓣植入术成本效益的现有证据体系，按所有风险类别进行分层，并评估其方法学质量。
方法
进行了一项系统评价，纳入已发表的心脏瓣膜植入术成本效益分析。采用卫生经济学工具质量评估法评估质量。
结果
我们确定了33项经导管主动脉心脏瓣膜植入术的经济评价。结果不一致，从占优到被占优。此外，模型对一系列变量敏感。研究的方法学质量良好。
结论
本系统评价得出了与经导管主动脉瓣置换术（TAVI）技术经济概况相关的不确定且不一致的结果。它还突出了在成本效益分析的支柱方面值得进一步研究的领域，如建模、现有数据的外推以及证据的不确定性。在任何决策之前都应全面评估患者情况。
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