Melo Isabela Martins, Nourouzi Darabad Masoud, Ramachandran Arun, Oquendo Paola Lourdes, Hamli Hesham, Lee Wei Wei, Nagel Flavia, Bansal Aditya, Muni Rajeev H
Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada.
Department of Ophthalmology, St. Michael's Hospital, Unity Health Toronto, Toronto, Ontario, Canada.
Data Brief. 2023 Jan 19;47:108920. doi: 10.1016/j.dib.2023.108920. eCollection 2023 Apr.
This article presents high-resolution swept-source optical coherence tomography (SS-OCT) imaging data used to elaborate a mechanical model that elucidates the formation of outer retinal corrugations (ORCs) in rhegmatogenous retinal detachments (RRD). The imaging data shared in the repository and presented in this article is related to the research paper entitled "Outer Retinal Corrugations in Rhegmatogenous Retinal Detachment: The Retinal Pigment Epithelium-Photoreceptor Dysregulation Theory" (Muni et al., AJO, 2022). The dataset consists of 69 baseline cross-sectional SS-OCT scans from 66 patients that were assessed for the presence of ORCs and analyzed considering the clinical features of each case. From the 66 cases, we selected SS-OCT images of 4 RRD patients with visible ORCs and no cystoid macular edema (CME) to validate the mechanical model. We modelled the retina as a composite material consisting of the outer retinal layer (photoreceptor layer) and the inner retinal layer (the part of the retina that excludes the photoreceptor layer) with thicknesses and and elastic modulus and , respectively. The thickness of the outer and inner retinal layers and the relative increase in the length of the outer retinal layer (γ) were measured from the SS-OCT images. Measurements from the SS-OCT images of patients with RRD demonstrated a 30% increase (γ=0.3) in the length of the outer retinal layer and a 400% increase in the thickness of the outer retinal layer (To). Using the mathematical model, Eo/Ei ranged between 0.05 to 0.5 to result in ORCs with a similar frequency to those observed in the SS-OCT scans.
本文展示了高分辨率扫频源光学相干断层扫描（SS-OCT）成像数据，这些数据用于构建一个力学模型，以阐明孔源性视网膜脱离（RRD）中外层视网膜皱褶（ORC）的形成机制。存储库中共享并在本文中呈现的成像数据与题为《孔源性视网膜脱离中的外层视网膜皱褶：视网膜色素上皮-光感受器失调理论》（穆尼等人，《美国眼科杂志》，2022年）的研究论文相关。该数据集由来自66名患者的69次基线横断面SS-OCT扫描组成，这些患者接受了ORC的评估，并根据每个病例的临床特征进行了分析。从这66例病例中，我们选择了4例有可见ORC且无黄斑囊样水肿（CME）的RRD患者的SS-OCT图像来验证力学模型。我们将视网膜建模为一种复合材料，由外层视网膜层（光感受器层）和内层视网膜层（视网膜中排除光感受器层的部分）组成，其厚度分别为 和 ，弹性模量分别为 和 。外层和内层视网膜层的厚度以及外层视网膜层长度的相对增加量（γ）是从SS-OCT图像中测量得到的。RRD患者的SS-OCT图像测量结果显示，外层视网膜层长度增加了30%（γ = 0.3），外层视网膜层厚度增加了400%（To）。使用该数学模型，Eo/Ei的范围在0.05至0.5之间，以产生与SS-OCT扫描中观察到的频率相似的ORC。
