左旋多巴治疗对帕金森病对比敏感度的影响。
Effect of levodopa treatment on contrast sensitivity in Parkinson's disease.
作者信息
Bulens C, Meerwaldt J D, Van der Wildt G J, Van Deursen J B
机构信息
Department of Neurology, Sint Franciscus Gasthuis, Rotterdam, The Netherlands.
出版信息
Ann Neurol. 1987 Sep;22(3):365-9. doi: 10.1002/ana.410220313.
We studied contrast sensitivity function in 10 parkinsonian patients before and after levodopa treatment. Pretreatment contrast sensitivity function was abnormal in 16 of the 20 eyes. After treatment, only high-frequency loss was observed in 6 eyes. All other types of deficit disappeared under treatment. These changes of contrast sensitivity function following treatment suggest that dopamine is a functional transmitter in the visual pathways.
我们研究了10例帕金森病患者在左旋多巴治疗前后的对比敏感度函数。20只眼中有16只眼治疗前对比敏感度函数异常。治疗后，仅6只眼观察到高频损失。治疗后所有其他类型的缺陷均消失。治疗后对比敏感度函数的这些变化表明多巴胺是视觉通路中的一种功能性递质。
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