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小儿急性鼻-鼻窦炎眼眶及颅内并发症的诊断与处理

[Diagnosis and management of orbital and cranial complications of pediatric acute rhinosinusitis].

作者信息

Yang X J, Tang L X, Wang P P, Cui Y H, Sun J H, Zhang W, Xiao X, Han Y, Ge W T

机构信息

Department of Otorhinolaryngology Head and Neck Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China.

Department of Ophthalmology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100045, China.

出版信息

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2023 Feb 7;58(2):133-138. doi: 10.3760/cma.j.cn115330-20220315-00114.

Abstract

To review the clinical characteristics, to illustrate diagnosis and management experience of orbital and cranial complications of pediatric acute rhinosinusitis. The clinical data of 24 children with orbital and cranial complications of acute rhinosinusitis who received endoscopic sinus surgery combined with drug treatment in Beijing Children's Hospital from January 2017 to December 2021 were retrospectively reviewed. There were 19 boys and 5 girls. The age varied from 13 to 159 months, with a median 47.5 months. The following diagnoses were obtained: 12 isolated subperiosteal orbital abscess, 2 associated with preseptal abscess, 2 associated with intraorbital abscess, 7 associated with optic neuritis, and 1 associated with septic cavernous sinus thrombosis. Clinical characteristics, organism isolated and outcomes were analyzed through descriptive methods. All 24 patients presented with fever; 9 presented with nasal congestion and purulent discharge. The clinical manifestations of orbital infection included orbital edema, pain, proptosis and displacement of globe in all patients, while visual impairment was recognized in 7 children. Purulent drainage was cultured in 17 patients, among which 12 were positive. All patients underwent nasal endoscopic surgical interventions uneventfully, excluding one patient who required a second surgical procedure. Follow-up period ranged from 5 to 64 months. All patients resolved fully, with the exception of 2 children who got permanent blindness with visual loss preoperative. There was no recurrence or death. Orbital and cranial complications of pediatric acute rhinosinusitis could be severe with an occult onset. For patients with vison impairment, any signs of intracranial complications and a lack of response to conservative management, an urgent endoscopic intervention is needed.

摘要

回顾小儿急性鼻窦炎眼眶及颅内并发症的临床特征,阐述其诊断及治疗经验。回顾性分析2017年1月至2021年12月在北京儿童医院接受鼻内镜鼻窦手术联合药物治疗的24例小儿急性鼻窦炎眼眶及颅内并发症患者的临床资料。其中男19例,女5例。年龄13至159个月,中位年龄47.5个月。诊断如下:孤立性骨膜下眼眶脓肿12例,合并眶隔前脓肿2例,合并眶内脓肿2例,合并视神经炎7例,合并感染性海绵窦血栓形成1例。采用描述性方法分析临床特征、分离出的病原体及治疗结果。24例患者均有发热;9例有鼻塞、脓性分泌物。眼眶感染的临床表现包括所有患者均有眼眶水肿、疼痛、眼球突出及眼球移位,7例患儿有视力障碍。17例患者进行了脓性分泌物培养,其中12例阳性。所有患者均顺利接受鼻内镜手术干预,1例患者需二次手术除外。随访时间5至64个月。除2例术前视力丧失导致永久性失明的患儿外,所有患者均完全康复。无复发及死亡病例。小儿急性鼻窦炎眼眶及颅内并发症可能很严重,起病隐匿。对于有视力障碍、任何颅内并发症迹象且对保守治疗无反应的患者,需要紧急进行内镜干预。

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