Department of Conservative Dentistry and Endodontics, Hitkarini Dental College, Jabalpur, India.
Department of Surgical Oncology, Saptrishi Hospital and Cancer Center, Jabalpur, India.
Eur Endod J. 2023 Jan;8(1):101-104. doi: 10.14744/eej.2022.29200.
Periapical lesions of endodontic origin are fairly common in the oral cavity in association with tooth pulp infection. Most of these lesions will resolve with adequate root canal treatment and rarely cause suspicion of more insidious disease. Most clinicians tend to skip histopathological examination in cases where the lesion is excised or curetted. We present a rare case of mucinous adenocarcinoma in association an endodontically treated maxillary discoloured central incisor in a 38 year old patient with a history of root canal treatment about 15 years ago. Root canal re-treatment and wide excision was performed. Histology showed epithelial islands suggestive of a neoplasm. Immunohistochemistry was positive for CK7 and S100. Metastasis was ruled out and no evidence of recurrence has been noted in the 12-month follow up period. It is emphasized that any tissue removed from the surgical site should be analysed microscopically. (EEJ-2022-01-013).
牙髓来源的根尖病变在口腔中较为常见,与牙髓感染有关。大多数这些病变在经过充分的根管治疗后会得到解决,很少引起对更隐匿性疾病的怀疑。大多数临床医生在切除或刮除病变时倾向于跳过组织病理学检查。我们报告了一例罕见的黏液性腺癌病例,该病例与一位 38 岁患者的上颌变色中央门牙有关,该患者 15 年前曾有根管治疗史。进行了根管再治疗和广泛切除。组织学显示上皮岛提示肿瘤。免疫组织化学 CK7 和 S100 阳性。排除了转移,在 12 个月的随访期间未发现复发的证据。强调从手术部位切除的任何组织都应进行显微镜分析。(EEJ-2022-01-013)。