Mankertz Annette, Chen Min-Hsin, Goldberg Tony L, Hübschen Judith M, Pfaff Florian, Ulrich Rainer G
Department of Infectious Diseases, Robert Koch-Institute, 13353 Berlin, Germany.
Viral Vaccine Preventable Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
J Gen Virol. 2022 Dec;103(12). doi: 10.1099/jgv.0.001817.
The family comprises enveloped viruses with positive-sense RNA genomes of 9.6-10 kb. The genus includes rubella virus (species ) infecting humans, ruhugu virus (species ) infecting bats and rustrela virus (species ) infecting rodents and zoo animals. Rubella virus is spread via droplets. Postnatal infection leads to benign disease with rash and fever. Infection of seronegative women with rubella virus during the first trimester of pregnancy will often result in severe foetal malformations, known as congenital rubella syndrome. Vaccines are globally available. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family which is available at ictv.global/report/matonaviridae.
该病毒科包含具有9.6 - 10 kb正链RNA基因组的包膜病毒。该属包括感染人类的风疹病毒(种)、感染蝙蝠的鲁胡古病毒(种)以及感染啮齿动物和动物园动物的鲁斯特雷拉病毒(种)。风疹病毒通过飞沫传播。出生后感染会导致伴有皮疹和发热的良性疾病。血清阴性的女性在妊娠头三个月感染风疹病毒通常会导致严重的胎儿畸形,即先天性风疹综合征。全球都有疫苗可用。这是国际病毒分类委员会(ICTV)关于该病毒科报告的摘要,可在ictv.global/report/matonaviridae获取。