Cardiovascular Research Center of Rajaei, Alborz University of Medical Sciences, Karaj, 3197635141, Iran.
Clinical Research Development Center of Rajaei, Alborz University of Medical Sciences, Karaj, 3197635141, Iran.
Future Cardiol. 2023 Jan;19(1):19-27. doi: 10.2217/fca-2022-0064. Epub 2023 Feb 7.
We aimed to compare in-hospital mortality (IHM) of acute myocardial infarction (AMI) between male and females. We assessed the association of sex with IHM after AMI using simple and multivariate cox regression models. Results were presented as crude and adjusted hazard ratios along with their 95% confidence interval (HR; 95% CI). Multivariable Cox regression analysis revealed females had a higher risk of death than males after ST-elevation MI (STEMI) (adjusted HR [95% CI]: 1.64 [1.15-2.36]; p = 0.007). In subgroup analysis by age group, this significantly increased risk was only observed in 50- to 64-year-old females. There were no significant differences between genders after non-STEMI and unspecified MI. Women aged 50 to 64 years had higher IHM after STEMI than men.
我们旨在比较男性和女性急性心肌梗死（AMI）患者的住院死亡率（IHM）。我们使用简单和多变量 Cox 回归模型评估了性别与 AMI 后 IHM 的相关性。结果以粗死亡率和调整后的危险比（HR）及其 95%置信区间（HR; 95%CI）呈现。多变量 Cox 回归分析显示，女性在 ST 段抬高型心肌梗死（STEMI）后死亡风险高于男性（调整后的 HR [95%CI]：1.64 [1.15-2.36]；p = 0.007）。在按年龄组进行的亚组分析中，仅在 50 至 64 岁的女性中观察到这种显著增加的风险。在非 STEMI 和未特指的 MI 后，性别之间没有显著差异。50 至 64 岁的女性 STEMI 后 IHM 高于男性。
