Sawada M, Inagaki M, Hirota Y, Hongo J, Ozaki M
Dept. of Gynecology, Center for Adult Diseases, Osaka.
Gan To Kagaku Ryoho. 1987 Nov;14(11):3091-4.
Thirteen patients with gynecologic cancer were treated with ifosfamide (2 g X 5), cisplatin (70 mg/m2) and adriamycin (20 mg/m2) combination chemotherapy. The response rate of 7 evaluable patients was 43%, with a median duration of survival of 14 months. Six patients with non-measurable disease are currently free from disease with a median duration of survival of 18 months. This combination caused reversible myelosuppression. No hemorrhagic cystitis was observed.
13例妇科癌症患者接受了异环磷酰胺（2g×5）、顺铂（70mg/m²）和阿霉素（20mg/m²）联合化疗。7例可评估患者的缓解率为43%，中位生存期为14个月。6例不可测量疾病患者目前疾病无进展，中位生存期为18个月。该联合治疗引起可逆性骨髓抑制。未观察到出血性膀胱炎。
