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异环磷酰胺、顺铂、阿霉素联合化疗在妇科癌症中的应用

[Ifosfamide, cisplatin, adriamycin combination chemotherapy in gynecologic cancer].

作者信息

Sawada M, Inagaki M, Hirota Y, Hongo J, Ozaki M

机构信息

Dept. of Gynecology, Center for Adult Diseases, Osaka.

出版信息

Gan To Kagaku Ryoho. 1987 Nov;14(11):3091-4.

PMID:3674894
Abstract

Thirteen patients with gynecologic cancer were treated with ifosfamide (2 g X 5), cisplatin (70 mg/m2) and adriamycin (20 mg/m2) combination chemotherapy. The response rate of 7 evaluable patients was 43%, with a median duration of survival of 14 months. Six patients with non-measurable disease are currently free from disease with a median duration of survival of 18 months. This combination caused reversible myelosuppression. No hemorrhagic cystitis was observed.

摘要

13例妇科癌症患者接受了异环磷酰胺(2g×5)、顺铂(70mg/m²)和阿霉素(20mg/m²)联合化疗。7例可评估患者的缓解率为43%,中位生存期为14个月。6例不可测量疾病患者目前疾病无进展,中位生存期为18个月。该联合治疗引起可逆性骨髓抑制。未观察到出血性膀胱炎。

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