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[血栓形成后综合征——一种复杂的临床症状]

[Postthrombotic syndome-a complex clinical picture].

作者信息

Kahle Birgit

机构信息

Klinik für Dermatologie, Venerologie und Allergologie, Universitäts-Klinikum Schleswig-Holstein (UKSH) Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Deutschland.

出版信息

Dermatologie (Heidelb). 2023 Mar;74(3):158-162. doi: 10.1007/s00105-023-05111-y. Epub 2023 Feb 7.

Abstract

Postthrombotic syndrome (PTS), which comprises a range of symptoms and signs following the development of deep vein thrombosis, is associated with varied clinical presentation. The functional limitations associated with PTS may be persistent, and following deep vein thrombosis, the patient may require lifelong anticoagulation. Venous ulceration is often regarded as a complication of PTS. However, the development of venous ulceration strictly depends on underlying venous hypertension, which is not always present. Due to the heterogenous clinical presentation of PTS, diagnosis may be difficult. Nevertheless, accurate diagnosis is vital and modern imaging techniques can help establish the diagnosis and play a role in monitoring treatment response. Thus, in addition to new strategies in compression therapy, (endo)vascular interventions are established treatment modalities in the management of PTS.

摘要

血栓形成后综合征(PTS)发生于深静脉血栓形成之后,包含一系列症状和体征,临床表现多样。与PTS相关的功能受限可能持续存在,深静脉血栓形成后,患者可能需要终身抗凝治疗。静脉溃疡常被视为PTS的一种并发症。然而,静脉溃疡的发生严格取决于潜在的静脉高压,而静脉高压并非总是存在。由于PTS临床表现的异质性,诊断可能存在困难。尽管如此,准确诊断至关重要,现代成像技术有助于确诊并在监测治疗反应中发挥作用。因此,除了压迫治疗的新策略外,(血管内)血管介入是PTS治疗中已确立的治疗方式。

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