Lechner W, Heim K, Zech J, Daxenbichler G, Marth C
Department of Obstetrics and Gynecology, University of Innsbruck, Austria.
Arch Gynecol Obstet. 1987;241(1):9-12. doi: 10.1007/BF00931435.
Specimens of saliva were obtained from 106 women with normal pregnancies and from 42 women, whose children turned out to small for dates (birthweight below the 10th centile). Saliva estriol was highly significantly (P less than 0.0001) decreased in the group with a newborn with a birthweight below the 10th centile (500 +/- 340 ng/ml, mean +/- SD) when compared with the group with infants whose birthweight was over the 10th centile (813 +/- 449 ng/ml). Estriol determination in saliva seems to be a simple, non invasive method of aiding the detection of fetal growth retardation.
从106名正常妊娠的妇女以及42名孩子出生体重低于孕龄标准（出生体重低于第10百分位数）的妇女身上采集了唾液样本。与出生体重高于第10百分位数的婴儿组（813±449纳克/毫升）相比，出生体重低于第10百分位数的新生儿组（500±340纳克/毫升，平均值±标准差）的唾液雌三醇水平显著降低（P<0.0001）。唾液雌三醇测定似乎是一种有助于检测胎儿生长迟缓的简单、非侵入性方法。
