Division of Infectious Diseases and Global Public Health, University of California San Diego. San Diego, United States.
Departamento de Estudios de Población, El Colegio de la Frontera Norte. Tijuana, Mexico.
Salud Publica Mex. 2023 Jan 2;65(1, ene-feb):10-18. doi: 10.21149/13980.
To interrogate the circulating SARS-CoV-2 lin-eages and recombinant variants in persons living in migrant shelters and persons who inject drugs (PWID).
We combined data from two studies with marginalized populations (migrants in shelters and persons who inject drugs) in Tijuana, Mexico. SARS-CoV-2 variants were identified on nasal swabs specimens and compared to publicly available genomes sampled in Mexico and California.
All but 2 of the 10 lineages identified were predomi-nantly detected in North and Central America. Discrepan-cies between migrants and PWID can be explained by the temporal emergence and short time span of most of these lineages in the region.
The results illustrate the temporo-spatial structure for SARS-CoV-2 lineage dispersal and the potential co-circulation of multiple lineages in high-risk populations with close social contacts. These conditions create the potential for recombination to take place in the California-Baja California border.
调查居住在移民收容所和注射毒品者（PWID）中的循环 SARS-CoV-2 谱系和重组变体。
我们结合了在墨西哥蒂华纳的两个边缘化人群（移民收容所中的移民和注射毒品者）的研究数据。在鼻拭子样本中鉴定了 SARS-CoV-2 变体，并将其与在墨西哥和加利福尼亚州采样的公开可用基因组进行了比较。
除了 10 个鉴定的谱系中的 2 个之外，其余均主要在北美和中美洲检测到。移民和 PWID 之间的差异可以通过该地区大多数这些谱系的时间出现和短时间跨度来解释。
结果说明了 SARS-CoV-2 谱系传播的时空结构，以及具有密切社会接触的高危人群中多种谱系的潜在共同循环。这些情况为加利福尼亚-下加利福尼亚边境的重组创造了潜力。
