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2018年,塞拉利昂弗里敦腹泻患者中抗生素耐药基因的传播情况

Dissemination of Antibiotic Resistance Genes Among Patients with Diarrhea - Freetown, Sierra Leone, 2018.

作者信息

Chen Xia, Zhang Enmin, Abdulai Michael K, Tia Alie Brima, Ngegba Esther Debora, Yin Jianhai, Xu Songtao, Wang Lili, Dong Xiaoping, Harding Doris, Kan Biao

机构信息

State Key Laboratory of Infectious Disease Prevention and Control, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing Municipality, China.

Sierra Leone-China Friendship Biological Safety Laboratory, Chinese Center for Disease Control and Prevention, Freetown, Sierra Leone and Beijing Municipality, China.

出版信息

China CDC Wkly. 2022 Dec 9;4(49):1093-1096. doi: 10.46234/ccdcw2022.221.

Abstract

WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: Antibiotic resistance (AR) is a serious public health threat worldwide. However, the AR and antibiotic resistance genes (ARGs) data from West Africa, especially from Sierra Leone, are limited.

WHAT IS ADDED BY THIS REPORT?: The study revealed ARGs' common dissemination, and multiplex antibiotic resistance genes in one sample. Genes and were first discovered in Sierra Leone.

WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE?: Basic information is provided for AR research and surveillance and highlights that effective AR surveillance among diarrhea patients is necessary for Sierra Leone and West Africa.

摘要

关于该主题已知的信息有哪些?:抗生素耐药性(AR)是全球范围内严重的公共卫生威胁。然而,来自西非,尤其是来自塞拉利昂的抗生素耐药性和抗生素耐药基因(ARGs)数据有限。

本报告补充了哪些内容?:该研究揭示了ARGs的普遍传播以及一个样本中的多重抗生素耐药基因。基因 和 首次在塞拉利昂被发现。

对公共卫生实践有何启示?:为AR研究和监测提供了基础信息,并强调对塞拉利昂和西非腹泻患者进行有效的AR监测是必要的。

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本文引用的文献

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Antimicrobial resistance in West Africa: a systematic review and meta-analysis.西非的抗微生物药物耐药性:系统评价和荟萃分析。
Int J Antimicrob Agents. 2017 Nov;50(5):629-639. doi: 10.1016/j.ijantimicag.2017.07.002. Epub 2017 Jul 11.

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