Gutierrez Juan Pablo, Johri Mira
National Autonomous University of Mexico Mexico City Mexico National Autonomous University of Mexico, Mexico City, Mexico.
Université de Montréal Montreal, Quebec Canada Université de Montréal, Montreal, Quebec, Canada.
Rev Panam Salud Publica. 2023 Jan 30;47:e35. doi: 10.26633/RPSP.2023.35. eCollection 2023.
To document the evolution of socioeconomic and geographical inequalities in childhood vaccination in Mexico from 2012 to 2021.
Repeated cross-sectional analysis using three rounds of National Health and Nutrition Surveys (2012, 2018, and 2021). Dichotomous variables were created to identify the proportion of children who received no dose of each vaccine included in the national immunization schedule (BCG; diphtheria, pertussis, and tetanus-containing; rotavirus; pneumococcal conjugate; and measles, mumps, and rubella [MMR]), and the proportion completely unvaccinated. The distribution of unvaccinated children was analyzed by state, and by socioeconomic status using the concentration index.
The prevalence of completely unvaccinated children in Mexico was low, with 0.3% children in 2012 and 0.8% children in 2021 receiving no vaccines ( = 0.070). Notwithstanding, for each vaccine, an important proportion of children missed receiving any dose. Notably, the prevalence of MMR unvaccinated children was 10.2% (95% CI 9.2-11.1) in 2012, 22.3% (95% CI 20.9-23.8) in 2018, and 29.1% (95% CI 26.3-31.8) in 2021 ( < 0.001 for the difference between 2012 and 2021). The concentration index indicated pro-rich inequalities in non-vaccination for 2 of 5 vaccines in 2012, 3 of 5 vaccines in 2018, and 4 of 5 vaccines in 2021. There were marked subnational variations. The percentage of MMR unvaccinated children ranged from 3.3% to 17.9% in 2012, 5.5% to 36.5% in 2018, and 13.1% to 72.5% in 2021 across the 32 states of Mexico.
Equitable access to basic childhood vaccines in Mexico has deteriorated over the past decade. Vigilant equity monitoring coupled with tailored strategies to reach those left out is urgently required.
记录2012年至2021年墨西哥儿童疫苗接种中社会经济和地理不平等情况的演变。
采用三轮全国健康与营养调查(2012年、2018年和2021年)进行重复横断面分析。创建二分变量以确定未接种国家免疫规划中每种疫苗(卡介苗;白喉、百日咳和破伤风联合疫苗;轮状病毒疫苗;肺炎球菌结合疫苗;麻疹、腮腺炎和风疹[MMR]疫苗)任何一剂的儿童比例,以及完全未接种疫苗的儿童比例。按州以及使用集中指数按社会经济地位分析未接种疫苗儿童的分布情况。
墨西哥完全未接种疫苗儿童的患病率较低,2012年为0.3%,2021年为0.8%(P = 0.070)。尽管如此,对于每种疫苗,仍有相当比例的儿童未接种任何一剂。值得注意的是,MMR疫苗未接种儿童的患病率在2012年为10.2%(95%置信区间9.2 - 11.1),2018年为22.3%(95%置信区间20.9 - 23.8),2021年为29.1%(95%置信区间26.3 - 31.8)(2012年与2021年之间的差异P < 0.001)。集中指数表明,2012年5种疫苗中有2种、2018年5种疫苗中有3种、2021年5种疫苗中有4种在未接种疫苗方面存在有利于富裕人群的不平等情况。存在明显的次国家级差异。在墨西哥的32个州中,2012年MMR疫苗未接种儿童的比例在3.3%至17.9%之间,2018年在5.5%至36.5%之间,2021年在13.1%至72.5%之间。
在过去十年中,墨西哥儿童基本疫苗的公平可及性有所恶化。迫切需要进行严格的公平性监测,并制定针对性策略以覆盖那些未接种疫苗的儿童。